2013
DOI: 10.1182/blood.v122.21.4643.4643
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Erythrocytosis Post Allogeneic Stem Cell Transplantation, An Observational Study Of Hemoglobin Levels On Long-Term Follow Up Post Transplantation In Patients With Fanconi Or Acquired Aplastic Anemia

Abstract: Post-transplant erythrocytosis is an ominous complication of kidney transplantation, occurring in the first 8 to 24 months after surgery in 10% to 15% of transplant recipients; this is frequently associated with significant thromboembolic events and sometimes death. In patients undergoing allogeneic hematopoietic cell transplantation (HCT), erythrocytosis has not been previously well described. At our institution, we observed that some aplastic anemia (AA), and Fanconi anemia (FA) patients developed progressiv… Show more

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“…Ayas et al presented the largest observational study about post‐transplant erythrocytosis in 17 pediatric patients who underwent allo‐HSCT due to Fanconi or acquired aplastic anemia. The median time to reach the highest hemoglobin level was 67 months in females and 103 months in males after allo‐HSCT . In our cases, peak hemoglobin level with median 56 months after the transplantation was observed earlier than in the Ayas et al study.…”
Section: Discussioncontrasting
confidence: 46%
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“…Ayas et al presented the largest observational study about post‐transplant erythrocytosis in 17 pediatric patients who underwent allo‐HSCT due to Fanconi or acquired aplastic anemia. The median time to reach the highest hemoglobin level was 67 months in females and 103 months in males after allo‐HSCT . In our cases, peak hemoglobin level with median 56 months after the transplantation was observed earlier than in the Ayas et al study.…”
Section: Discussioncontrasting
confidence: 46%
“…On univariate analysis of Ayas et al study, patients of an older age at HCT were more likely to develop erythrocytosis, whereas those with radiation in the conditioning regimen were less associated with high hemoglobin levels. None of the patients reported any clinical symptoms during the follow‐up visits and thromboembolic events .…”
Section: Discussionmentioning
confidence: 99%
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