ESCC with Metastasis in the Young Age of Caustic Ingestion of Shortest Duration

Jain, Rohit; Gupta, Shubha; Pasricha, Nidhi; Faujdar, Mansi; Sharma, Meenakshi; Mishra, Pradeep

doi:10.1007/s12029-009-9121-8

Cited by 23 publications

(17 citation statements)

References 11 publications

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“… 23 ESCC can present within the first year of exposure to a corrosive agent or up to 40 years later. 24 , 25 The mechanism associated with the development of ESCC due to caustic agents is related to the chronic inflammation they condition, as well as to the local damage they produce.…”

Section: Risk Factors For Esccmentioning

confidence: 99%

Achalasia and esophageal cancer: risks and links

Torres-Aguilera¹,

Troche²

2018

CEG

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Esophageal cancer affects more than 4,50,000 persons worldwide, and its incidence has increased in recent years. It is the eighth most common cancer across the globe. The main histologic types are esophageal squamous cell carcinoma (ESCC) and esophageal adenocarcinoma (EA), and their associated risk factors are well known. Achalasia, an idiopathic esophageal disorder that conditions aperistalsis and the absence of lower esophageal sphincter relaxation, stands out among them. The prevalence of ESCC in subjects with esophageal achalasia is 26 in every 1,000 cases, whereas the prevalence of EA is 4 in every 1,000. Patients with achalasia have a 50 times higher risk of presenting with ESCC than the general population, and the disease manifests 20–25 years after achalasia symptom onset. Multiple mechanisms are related to the development of ESCC in achalasia, and they include bacterial overgrowth, food stasis, genetic alterations, and chronic inflammation. Regarding the risk of EA in achalasia patients, most cases are associated with Barrett’s esophagus, due to uncontrolled chronic acid reflux. Given that achalasia is a well-established factor for ESCC/EA, clinicians must be aware of said associations to enable the development of programs for the prevention and opportune detection of these cancers in patients with achalasia.

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Section: Risk Factors For Esccmentioning

confidence: 99%

Achalasia and esophageal cancer: risks and links

Torres-Aguilera¹,

Troche²

2018

CEG

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“…In 3 patients, SCC after caustic injury (due to lye ingestion in one case and due to unknown agents in 2 cases) occurred after a latency of 1, 10 and 12 years, respectively, after ingestion [17, 21, 29]. …”

Section: Resultsmentioning

confidence: 99%

“…Ingestion of caustic agents and history of smoking, two well-defined pathogenic factors for SCC, were only reported in five cases [13, 17, 21, 29, 32]. SCC developed 1, 10 and 12 years after caustic injury and after 3 and 5 years of cigarette smoking.…”

Section: Discussionmentioning

confidence: 99%

Esophageal adenocarcinoma and squamous cell carcinoma in children and adolescents: Report of 3 cases and comprehensive literature review

Theilen

Chou

Klimstra

et al. 2016

Journal of Pediatric Surgery Case Reports

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“…1 Ne yazık ki 14 yaşındaki bir çocukta korozif madde içiminden sadece 1 yıl sonra ölümcül skuamöz hücreli özofagus karsinomu geliştiği de görülmüştür. 58 Şu ana kadar ki yayınlardan, belki de buzdağının altı, bu büyük sorunun göz ardı edildiği ve ailelere bu konuda çoğunlukla yeteri kadar bilgi verilmediği anlaşılmaktadır. Bu konuda uzun dönem sonuçları araştıran yazılara şiddetle gereksinim duyulmaktadır.…”

Section: Korozif Madde İçimi Yönetimiunclassified

Corrosive Substance Ingestion in Children: A Current Evaluation and Treatment Approach

Uygun¹

2018

Turkiye Klinikleri J Pediatr

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RESİM 1: Bazı açıkta satılan tehlikeli korozif maddeler (A-F). (A): su kaplarına konularak açıkta satılan sıvı korozif maddeler; (B, C): Mahalle pazarlarında (B) orijinal sirke ruhu (C1) ve hakiki Siirt sirkesi gibi isimlerle satılan ve turşu yapımında kanunen yasak olmasına karşın kullanılan asetik asit (C1 ve C2) normal pet şişe suyuna (C3) çok benzemektedir; (D): Sülfürik asit içeren çocuk korumalı kapaksız akü asidi (D1) ile akü için saf su (D2) yanyana satılmaktadır; (E): Korozifler gıdalar ile birlikte pet su şişesinde; E1: kireç çözücü; E2: çamaşır suyu; E3: deterjan, (F): Kostik etiketi ile merdiven altı üretilmiş güçlü alkali sodyum hidroksit içeren yağ çözücü.

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ESCC with Metastasis in the Young Age of Caustic Ingestion of Shortest Duration

Abstract: Accidental caustic ingestion may have an unusual presentation and severe complications, but a favorable outcome. Guidance and education are important preventive tools, but the best approach is to restrict access to caustic agents by prohibiting their free commercialization.

Cited by 23 publications

References 11 publications

Achalasia and esophageal cancer: risks and links

Achalasia and esophageal cancer: risks and links

Esophageal adenocarcinoma and squamous cell carcinoma in children and adolescents: Report of 3 cases and comprehensive literature review

Corrosive Substance Ingestion in Children: A Current Evaluation and Treatment Approach

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