Essential laboratory tests for medical education

Deyrup, Andrea T.; Knollmann-Ritschel, Barbara; D'Ambrosio, Danielle; Muir, Jeannie M.; Scordino, Teresa; Kraswoski, Matthew; Cao, Liyun; Shah, Kinjal S; Zepf, Jennifer; Grindstaff, Samuel; Inman, Ashley; Moser, Karen; Olson, Kristin; Parker, Lynette; Shmookler, Aaron; Ou, Joyce; Putnam, Angelica R.; Watts, Luisa; Betts, Elham Vali; Lovitch, Scott B.; Stashek, Kristen; Flanagan, Melina; Singh, Nirupama; Gálvez-Suárez, Eric; Dudrey, Ellen; Furlong, Mary A.; Márta, Mészáros; Wilberger, Adam; Chan, Joanna; Lin, Amy

doi:10.1016/j.acpath.2022.100046

Cited by 4 publications

(3 citation statements)

References 35 publications

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“…A recent publication highlighting the most common laboratory tests and the pathophysiology underlying changes in their values has been linked to the PCME. 5 …”

Section: Discussionmentioning

confidence: 99%

“…In order to decide whether an objective merited inclusion we used standard pathology textbooks and a recent comprehensive reference to assess whether information was necessary to include. 3 , 4 , 5 As Fig. 1 illustrates, the revision of the PCME is a cyclic process that includes incorporation of comments from constituents through multiple processes mentioned above.…”

Section: Methodsmentioning

confidence: 99%

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Pathology Competencies in Medical Education and Educational Cases: Update 2023

et al. 2023

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“…A recent publication highlighting the most common laboratory tests and the pathophysiology underlying changes in their values has been linked to the PCME. 5 …”

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Pathology Competencies in Medical Education and Educational Cases: Update 2023

et al. 2023

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“…[28] Hemoglobin variants, such as hemoglobin S (HbS) in SCA, can interfere with accurate glucose monitoring, including methods like Hemoglobin A1c (HbA1c) and fingerstick blood glucose tests. [29] These variants can lead to misleading glucose readings, potentially causing difficulties in regulating insulin or other diabetes medications, thereby increasing the risk of hypoglycemia or hyperglycemia due to misinterpretation of blood sugar levels. SCA is characterized by vaso-occlusive crises, where blood flow is obstructed by sickled red blood cells.…”

Section: Increased Risk Of Hypoglycemia Of Dm In Scamentioning

confidence: 99%

Management of diabetes mellitus patients with sickle cell anemia: Challenges and therapeutic approaches

Obeagu,

Obeagu

2024

Medicine

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The coexistence of diabetes mellitus (DM) and sickle cell anemia (SCA) poses significant challenges in clinical management due to the complex interactions and overlapping complications associated with both conditions. Managing diabetes in individuals with SCA requires a comprehensive approach that addresses the unique physiological and pathological aspects of both diseases. This paper reviews the challenges encountered in the management of DM in patients with SCA and explores therapeutic strategies and approaches to optimize patient care. Challenges in the management of DM in individuals with SCA stem from several factors, including the impact of hemoglobin variants on glycemic control assessment, increased susceptibility to infections, altered immune response, and complications associated with both diseases. Moreover, the coexistence of SCA and DM heightens the susceptibility to infections due to compromised immune function, emphasizing the need for vigilant preventive measures, including vaccinations and close monitoring for infectious complications. Close collaboration among healthcare providers specializing in diabetes, hematology, and other relevant fields is crucial for developing comprehensive care plans. Individualized treatment strategies that balance glycemic control, pain management, and preventive care are essential to mitigate complications and optimize the overall health outcomes of patients with both DM and SCA. In conclusion, managing diabetes in the context of SCA necessitates a nuanced and patient-centered approach. By addressing the challenges and employing tailored therapeutic strategies, healthcare providers can improve the quality of life and health outcomes for individuals affected by both conditions.

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