Essential Oil Composition of Three<i>Sideritis</i>Species Used as Herbal Teas in Turkey

Özkan, Gülcan; Krüger, Hans; Schulz, Hartwig; Özcan, Mehmet Musa

doi:10.1080/0972060x.2005.10643439

Cited by 8 publications

(7 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In previous studies, the essential oil composition of S. pisidica was reported [19][20][21][22]. In these studies, α-pinene, β-pinene, myrcene, α-bisabolol, sabinene, β-caryophyllene, eugenol, thymol and camphor were identified as major compounds.…”

Section: Essential Oil Compositionmentioning

confidence: 99%

“…There are some chemical studies performed on S. pisidica. Up to date, the essential oil [19][20][21][22] and fatty acid [23] compositions of S. pisidica have been studied. Also, antioxidant, antiacetylcholinesterase activity and phenolic composition of the aqueous and ethanolic extract of S. pisidica have been reported by Erdogan-Orhan et al [24] and Özkan [12].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chemical composition, antioxidant, anticholinesterase and anti-urease activities of Sideritis pisidica Boiss. Heldr. endemic to Turkey

Deveci¹,

Tel‐Çayan²,

Yıldırım³

et al. 2017

mpj

View full text Add to dashboard Cite

The objective of this study was to investigate the chemical composition, antioxidant, anticholinesterase and anti-urease activities of essential oil, hexane, acetone and methanol extracts of Sideritis pisidica Boiss. & Heldr. The essential oil and fatty acid composition were analyzed by GC and GC/MS. δ-Cadinene (19.5 %), T-cadinol (16.7 %) and β-cubebene (10.4 %) were identified as the main compounds of the essential oil whereas the most abundant compounds of fatty acids were found as linolenic (42.7 %), palmitic (31.3 %) and linoleic (13.4%) acids. The methanol extract demonstrated the highest antioxidant activity in all tests, except for metal chelating assay. The hexane extract was found to be significantly active in metal chelating (IC 50 : 22.97±1.36 µg/mL), acetylcholinesterase (62.54±0.88 %) and urease inhibitory (78.93±0.17 %) assays. These results show that the Sideritis pisidica could be used as the potential source of natural products in the food and pharmaceutical areas.

show abstract

Section: Essential Oil Compositionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Chemical composition, antioxidant, anticholinesterase and anti-urease activities of Sideritis pisidica Boiss. Heldr. endemic to Turkey

Deveci¹,

Tel‐Çayan²,

Yıldırım³

et al. 2017

mpj

View full text Add to dashboard Cite

show abstract

“…The essential oil yield in terms of dry weight basis, in general, for all Sideritis genus species is considerably low, in contrast with other Lamiaceae family genera [1]. There is a reported yield of S. perfoliata from Turkey as low as 0.08% [68]. Kirimer et al [69] reported the yield of many Sideritis species varying from traces to 0.85%, with S. perfoliata ranging from 0.12% to 0.36%.…”

Section: Resultsmentioning

confidence: 99%

“…Loizzo et al [67] also found high percentages of β-phelladrene (32.85%), sabinene (12.76%), α and β-pinene (8.66% and 8.90%) when essential oils from S. perfoliata sampled in Lebanon were analyzed, in accordance with the analysis presented here. However, there are studies on Sideritis reporting differences between the components and their participation in the oil chromatograph [55,68].…”

Section: Resultsmentioning

confidence: 99%

Sideritis Perfoliata (Subsp. Perfoliata) Nutritive Value and Its Potential Medicinal Properties

et al. 2019

View full text Add to dashboard Cite

Sideritis perfoliata L. subsp. perfoliata is an endemic species of the Eastern Mediterranean region with several uses in traditional medicine. The present study aims to explore the unknown properties of S. perfoliata investigating the nutritional content as well as the antioxidant, anticancer, antituberculosis, antiwrinkle, anti-acne, hyper/hypo-pigmentation and antibacterial activities. Mineral content, nutritional value, the composition and antioxidant properties of the essential oil, the antityrosinase, the antibacterial activity and anti-elastase potential of the extract, were evaluated. The antiproliferative activity of S. perfoliata against cervical cancer (HeLa), human melanoma (UCT-Mel-1), human hepatocellular carcinoma (HepG2) and human epidermoid carcinoma (A431) was investigated. Cytotoxic effects on normal human keratinocyte (HaCat) and kidney epithelial (Vero) cell lines were also determined. Sideritis perfoliata exhibited high nutritional value of proteins and minerals (K, P, Mg, Fe, Zn, Cu). The most abundant components of the essential oil were found to be α-pinene, β-phelladrene, valeranone, β-pinene and sabinene. The ethanolic extract of S. perfoliata displayed moderate antioxidant potential and antibacterial activity against Prevotella intermedia. Noteworthy elastase and moderate anticancer potential against the human liver cancer cell line (HepG2) was observed with IC50 values of 57.18 ± 3.22 μg/mL and 64.27 ± 2.04 μg/mL respectively. The noteworthy in vitro activity of S. perfoliata could be due to the presence of flavonoids and phenols in the leaves, having high nutritional value. Sideritis perfoliata could potentially be useful to reduce the appearance of wrinkles and for the treatment of liver cancer. The moderate antibacterial, antioxidant and elastase activity of the plant can be linked to the traditional use of S. perfoliata for the treatment of wounds and inflammation.

show abstract

“…The typical chemical constituents of the Sideritis genus are flavonoids [14,15], iridoids [16], coumarins, lignans [17], phenylpropanoid glycosides [18], and sterols [19]. Almost every species of Sideritis contains diterpenes [20], flavonoids [21], and essential oil [22,23], and with regard to the literature data, these constituents are responsible for the main pharmacological activities.…”

mentioning

confidence: 99%

Dual Excitatory and Smooth Muscle-relaxing Effect of Sideritis montana Extract on Guinea-pig Ileum

Tóth

Barthó

Vasas

et al. 2015

Natural Product Communications

View full text Add to dashboard Cite

The neuronal and smooth muscle effects of a methanol extract prepared from the air-dried flowering aerial parts of Sideritis montana L. (SME) was tested in vitro on Guinea-pig ileum. The chemical composition of the investigated extract was analysed by HPLC-MS, and chrysoeriol, chlorogenic acid and caffeic acid were detected as main constituents. The isolated organ assay showed that S. montana extract caused an immediate contraction and a more slowly developing inhibitory response in the ileum. The SME-induced contractions were strongly inhibited by the acetylcholine muscarinic receptor antagonist atropine (0.5 μM), but not by either the Na+ channel blocker tetrodotoxin (TTX; 0.5 μM) or the histamine H1 receptor antagonist chloropyramine (0.5 μM). Selective desensitization of capsaicin-sensitive neurons by the sensory neuron stimulant and blocker capsaicin did not influence the contractile effect of SME. As to the spasmolytic effect, SME inhibited the effects of electrical field stimulation, exogenous acetylcholine, and histamine. These smooth muscle-relaxing effects were reversible in 40 min by repeated renewals of the bathing solution.

show abstract

Essential Oil Composition of ThreeSideritisSpecies Used as Herbal Teas in Turkey

Cited by 8 publications

References 18 publications

Chemical composition, antioxidant, anticholinesterase and anti-urease activities of Sideritis pisidica Boiss. Heldr. endemic to Turkey

Chemical composition, antioxidant, anticholinesterase and anti-urease activities of Sideritis pisidica Boiss. Heldr. endemic to Turkey

Sideritis Perfoliata (Subsp. Perfoliata) Nutritive Value and Its Potential Medicinal Properties

Dual Excitatory and Smooth Muscle-relaxing Effect of Sideritis montana Extract on Guinea-pig Ileum

Contact Info

Product

Resources

About