Essential Oils and Crude Extracts from Chrysanthemum trifurcatum Leaves, Stems and Roots: Chemical Composition and Antibacterial Activity

Sassi, Ahlem Ben; Harzallah‐Skhiri, Fethia; Chraief, Imed; Bourgougnon, Nathalie; Hammami, Mohamed; Aouni, Mahjoub

doi:10.5650/jos.ess13228

Cited by 19 publications

(12 citation statements)

References 40 publications

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“…macrocephalum. The oil and methanolic extact from C. trifurcatum leaves showed a great potential of antibacterial effect against Bacillus subtilis and Staphylococcus epidermidis, with an IC50 range of 31.25-62.5 µg/ml 57 It can be considered that linarin is one of the promising active compounds effective against anxiety, insomnia, and stress, with acacetin as its active moiety 63 . The Chrysanthemum lavandulifolium extract, which includes chrysoeriol, Kim et al, 2013 sudachitin, and acacetin, has challenging antibiotic effects on Escherichia coli O157:H7 (E. coli O157).…”

Section: Key Findings Referencementioning

confidence: 99%

An Up-to-Date Review of Phytochemicals and Biological Activities in Chrysanthemum spp

Chae¹

2016

Biosci., Biotech. Res. Asia

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The Chrysanthemum is a well-known traditional Chinese medicinal herb which has been used as a drug for thousands of years. From the detailed literature survey it is determined that the dried flowers of Chrysanthemum contain organic groups such as alkanes, flavonoids, terpinoids, unsaturated fatty acids and polysaccharides which belongs to Secondary constituents in Phytochemicals classification. The knowledge and analysis of bioactive compounds present in the Chrysanthemums can be used for next generation drug development process. The developments of new drugs against diabetes and prostate cancer have become global concern. Hence the present study leads to identify the new strategies which are needed to develop multi-functional drugs against various human diseases using Chrysanthemum plant. Owing to antifungal, antibacterial and anti-inflammation activities, Chrysanthemum have much attention in the field of biomolecules research. In general Phytochemicals can be classified as primary and secondary constituents. One can understand the fascinating properties of biological compounds via phytochemical analysis which are present in the plants. Therefore, the present study gives a better understanding of phytochemical properties of Chrysanthemum and new foundations for the production of non-toxic and eco-friendly drugs of today and the future.

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Section: Key Findings Referencementioning

confidence: 99%

An Up-to-Date Review of Phytochemicals and Biological Activities in Chrysanthemum spp

Chae¹

2016

Biosci., Biotech. Res. Asia

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“…It has long been prescribed for the treatment of eye diseases in Chinese traditional preparations. Recent studies have shown that flavonoids in chrysanthemum are more likely to contribute to curing eye diseases [1] , [21] , [23] , [30] , [41] . Despite of recent progress, the definite component of chrysanthemum and the mechanism of action in the way chrysanthemum contributes to vision remains to be elucidated.…”

Section: Introductionmentioning

confidence: 99%

Diosmetin protects against retinal injury via reduction of DNA damage and oxidative stress

et al. 2016

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Visual impairment is a global public health problem that needs new candidate drugs. Chrysanthemum is a traditional Chinese drug, famous for its eye-protective function, with an unclear mechanism of action. To determine how chrysanthemum contributes to vision, we identified, for the first time, the component of chrysanthemum, diosmetin (DIO), which acts in protecting the injured retina in an adriamycin (ADR) improving model. We observed that DIO could attenuate the apoptosis of retinal cells in Sprague–Dawley rats and verified this effect in cultured human retinal pigment epithelium (RPE) cells, ARPE-19. Our further study on the mechanism revealed the counteractive effect of DIO on the attenuation of DNA damage and oxidative stress, which occurs in a wide range of retinal disorders. These results collectively promise the potential value of DIO as a retinal-protective agent for disorders that lead to blindness. In addition, we identified, for the first time, the component of chrysanthemum, DIO, which acts in protecting the injured retina.

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“…Studies have also shown that chrysanthemum polysaccharide can improve colitis and functional constipation in rats by regulating intestinal microbes [ 20 , 21 , 22 , 23 ]. While the chrysanthemum stem and leaf contain the main chemical components that are similar to chrysanthemum, including flavonoids, polysaccharides, phenolic acids, volatile oils and terpenoids [ 24 , 25 , 26 ], it is reported that the chrysanthemum stem regulates gastrointestinal function [ 27 , 28 ]. However, anti-inflammatory and antioxidant effects and the mechanisms of the chrysanthemum stem and leaf are rarely elucidated.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Anti-Inflammatory and Antioxidant Effectsof Chrysanthemum Stem and Leaf Extract on Zebrafish Inflammatory Bowel Disease Model

Liu

et al. 2022

Molecules

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Present studies have shown that Flos Chrysanthemi has anti-inflammatory and other effects and regulates intestinal function, while the chrysanthemum stem and leaf as non-medicinal parts of chrysanthemum have similar chemical components with chrysanthemum, but the activity and mechanisms are rarely elucidated. Therefore, this study used a DSS-induced zebrafish inflammatory bowel disease model to study the anti-inflammatory and antioxidant effects of chrysanthemum stem and leaf extracts. The results indicate that DSS induction leads to increased secretion of acidic mucin in the intestines of juvenile fish, enlargement of the intestinal lumen and the emergence of intestinal inflammation. Compared with the model group, each administration group differentially inhibited the expression of IL-1β, IL-8 and MMP9 in DSS-induced zebrafish, while upregulating the activity of superoxide dismutase. The quantitative analysis results showed that the flavonoids (including Linarin, Diosmetin-7-glucoside, Tilianin, etc.) and phenolic acids (including Isochlorogenic acid C, Isochlorogenic acid A, 1,3-Dicaffeoylquinic acid, etc.) in the alcohol extract were closely related with both anti-inflammatory and antioxidant activity, while the polysaccharides were also shown a certain anti-inflammatory and antioxidant activity. In conclusion, this study suggests that the flavonoids, phenolic acids and polysaccharides from chrysanthemum stem and leaf extracts can improve inflammatory bowel disease of zebrafish by regulating the expressions of IL-1β, IL-8 and MMP9.

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Essential Oils and Crude Extracts from Chrysanthemum trifurcatum Leaves, Stems and Roots: Chemical Composition and Antibacterial Activity

Cited by 19 publications

References 40 publications

An Up-to-Date Review of Phytochemicals and Biological Activities in Chrysanthemum spp

An Up-to-Date Review of Phytochemicals and Biological Activities in Chrysanthemum spp

Diosmetin protects against retinal injury via reduction of DNA damage and oxidative stress

Evaluation of Anti-Inflammatory and Antioxidant Effectsof Chrysanthemum Stem and Leaf Extract on Zebrafish Inflammatory Bowel Disease Model

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