Essential parameters and risk factors of the patients for diabetes care and treatment

Bener, Abdülbari; Keskin, Fatma Ela; Kurtulus, Eda Merve; Güzel, Mustafa; Çekirdekçi, Elif İjlal; Kadıoğlu, Pınar; Konukoğlu, Díldar; Öztürk, Mustafa

doi:10.1016/j.dsx.2017.03.008

Cited by 11 publications

(21 citation statements)

References 18 publications

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“…A number of studies have evaluated patient satisfaction using the DTSQ [18]. However, in almost of those reports, treatment satisfaction was assessed in patients The changes in values from baseline to week 12 are expressed as mean ± standard deviation.…”

Section: Discussionmentioning

confidence: 99%

Satisfaction and efficacy of switching from daily dipeptidyl peptidase-4 inhibitors to weekly trelagliptin in patients with type 2 diabetes—Randomized controlled study—

et al. 2018

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Abstract. We compared treatment satisfaction between daily dipeptidyl peptidase-4 (DPP-4) inhibitors and a weekly DPP-4 inhibitor in patients with type 2 diabetes. The study was a 12-week, open-label, randomized, multicenter, controlled trial. Participants were Japanese patients with type 2 diabetes who had received daily DPP-4 inhibitors for more than 3 months. Patients were randomly assigned to a treatment cohort: (1) a group that continued taking daily DPP-4 inhibitors (daily group); or (2) a group that switched from daily DPP-4 inhibitors to a weekly DPP-4 inhibitor, trelagliptin (weekly group). The primary outcome was the change in treatment satisfaction levels from baseline to 12 weeks between the two groups, according to Diabetes Treatment Satisfaction Questionnaire (DTSQ) and Diabetes Therapy-Related Quality of Life (DTR-QOL) questionnaire scores. The changes in glycemic control and body weight were also assessed. Of 49 patients initially enrolled in the study, 47 completed the study. The change in DTSQ scores in the weekly group was not significantly different from that in the daily group. However, the improvements in total score and subscale domains 1 and 2 in the DTR-QOL analysis, which relate to burden on social/daily activities and anxiety/dissatisfaction with treatment, were significantly greater in the weekly group than the daily group (p = 0.048, 0.013 and 0.045, respectively). Mean changes in glycated hemoglobin levels and body weight were comparable between the groups. Switching from daily DPP-4 inhibitors to a weekly DPP-4 inhibitor, trelagliptin, could partially improve treatment satisfaction levels in patients with type 2 diabetes without affecting glycemic control.

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Section: Discussionmentioning

confidence: 99%

Satisfaction and efficacy of switching from daily dipeptidyl peptidase-4 inhibitors to weekly trelagliptin in patients with type 2 diabetes—Randomized controlled study—

et al. 2018

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“…The etiology of T2DM is complex and includes abnormalities in multiple organs, including liver, skeletal muscle, adipocytes, gut, and beta cell [ 1 , 2 ]. T2DM also is a major risk factor for cardiovascular disease [ 3 , 4 ] which is the leading cause of death in western countries [ 5 , 6 ]. Several modifiable lifestyle factors, e.g., sleep duration, physical activity, and healthy-balanced diet can reduce the incidence of T2DM among high risk individuals [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

The Impact of Vitamin D Deficiency on Retinopathy and Hearing Loss among Type 2 Diabetic Patients

Bener

Eliacik

Cincik

et al. 2018

BioMed Research International

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Aim The current study was aiming to investigate the relation between vitamin D, retinopathy, and hearing loss among type 2 diabetes mellitus (T2DM) patients. Methods Cross-sectional study carried on 638 subjects aged between 20 and 60 years who visited the Endocrinology, Ophthalmology, and ENT Outpatient Clinics of the Medipol Hospital during the period from March 2016 to May 2017. Two audiometers Grason Stadler GSI 61 and Interacoustics AC40 Clinical audiometer were used to evaluate the hearing loss. Risk factors for diabetic retinopathy were evaluated, including age, sex, diabetes duration, glycated hemoglobin (HbA1c), hypertension, and lipid profiles. Results The mean age (± SD, in years) for retinopathy with hearing loss versus normal subjects was 47.7 ±10.2 versus 48.5±9.1. The associated risk factors were significantly higher in T2DM with hearing loss, hypertension (32.6% versus 15.7%), tinnitus (40.0% versus 18.0%), vertigo (59.7% versus 26.8%), and headache (54.9% versus 45.3%), than in normal hearing diabetes. There were statistically significant differences between hearing impairment versus normal hearing for vitamin D [19.40±9.71 ng/ml versus 22.67±9.28 ng/ml; p<0.001], calcium, magnesium, phosphorous, cholesterol, HDL-C, LDL-C, albumin, systolic blood pressure [131.70±9.25 Hg versus 127.73±11.98 Hg], diastolic blood pressure [82.20±8.60 mm Hg versus 79.80±8.20 mm Hg], and microalbuminuria. Multivariate logistic regression analysis revealed that variables such as vertigo, duration of DM, mobile/I pad phone, vitamin D deficiency, sleeping disturbance, headache, frequently TV watching, tinnitus, cigarette smokers, and hypertension were considered at higher risk as a predictors of retinopathy with hearing loss among diabetic patients. Conclusion Vitamin D deficiency is considered as a risk factor for diabetic retinopathy and hearing loss among diabetic patients. Meanwhile, hyperglycemia could be considered as a modifiable risk factor for diabetic retinopathy; tight glycemic control may be the most effective and important therapy for improving quality of life and substantially reducing the incidence of retinopathy and in T2DM patients.

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“…6 Studies examining the clinical efficacy of different types of DM treatment models have shown the importance of treatment satisfaction, since greater satisfaction has been found to be correlated with higher rates of compliance and better clinical outcomes. [7][8][9] Some authors found that having any diabetes-related complication was associated with lower satisfaction scores. [7][8][9][10][11] Biderman et al also noted that foot ulcers were associated with the lowest treatment satisfaction.…”

Section: Discussionmentioning

confidence: 99%

“…[7][8][9] Some authors found that having any diabetes-related complication was associated with lower satisfaction scores. [7][8][9][10][11] Biderman et al also noted that foot ulcers were associated with the lowest treatment satisfaction. 7 Furthermore, they found that patients taking oral hypoglycaemic agents were more satisfied than those taking the same drugs plus insulin.…”

Section: Discussionmentioning

confidence: 99%

Inpatient management of diabetes mellitus with poor glycaemic control: determinants of therapeutic success

Magalhães¹,

Furtado²,

Saavedra³

et al. 2018

EMIJ

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Background Diabetes mellitus (DM) is a chronic disease with an increasing prevalence worldwide, involving both sexes and all ages. In 2015, the estimated prevalence of DM in the Portuguese population aged between 20 and 79 years (7.7 million individuals) was 13.3%, namely more than 1 million. Moreover, 5.8% were previously unaware of the diagnosis. Globally, and in the same year, it was estimated that 415 million people, one in every 11 adults, suffered from DM. 1 The increasing incidence of DM and prediabetes represents a leading public health problem, concerning the entire medical community and health care systems around the world. Every day, endocrinologists face the challenge of trying to condense a large volume of complex information and practical skills into something useful for a population that is often illiterate and scarce in their abilities. The high number of consults and the reduced time for individual evaluation often makes it difficult to overcome. When attempts to educate patients about their disease, self-care

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Essential parameters and risk factors of the patients for diabetes care and treatment

Cited by 11 publications

References 18 publications

Satisfaction and efficacy of switching from daily dipeptidyl peptidase-4 inhibitors to weekly trelagliptin in patients with type 2 diabetes—Randomized controlled study—

Satisfaction and efficacy of switching from daily dipeptidyl peptidase-4 inhibitors to weekly trelagliptin in patients with type 2 diabetes—Randomized controlled study—

The Impact of Vitamin D Deficiency on Retinopathy and Hearing Loss among Type 2 Diabetic Patients

Inpatient management of diabetes mellitus with poor glycaemic control: determinants of therapeutic success

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