Estimate some immunoglobulin's and complement cascade in pregnant women suffering from urinary tract infection

Abstract

The objective of this study is a measurement of some immunoglobulin's (IgM and IgG) and complement cascade (C3, C4) in pregnant women suffering from urinary tract infections (UTI) by single radial Immunodiffusion test 30 samples of urine and the blood were collected from pregnant female infected by UTI and 10 specimens were collected from healthy pregnant women in the period from December 2020 to June 2021 the samples were taken from pregnant female and they're aged ranging from 18 to 30 years. The results of the study showed that the levels of IgG is higher in those with UTI the mean is in the three trimesters respectively than in control and there's a statistically significant in the first trimester only with P≤0.05. In UTI patients, the results appeared a elevate in the level of C3 and C4 in those with UTI is higher in the first and third trimester, however, it's slightly lower in UTI patients than in control in the second trimester, there's no statistical significance between those with UTI and control. Otherwise, the results demonstrated that the level of hepcidin in UTI patients increased compared with control in the first, second and third trimesters respectively.