Estimated glomerular filtration rate on postoperative day 1 is associated with renal functional outcome after percutaneous renal cryoablation for renal tumors

Early trends and predictors of renal function following computed tomography-guided percutaneous cryoablation of a renal mass in patients with and without prior renal impairment

“…However, it is difficult to determine whether tumor size or baseline GFR is a better individual predictor of postoperative renal function, because they are probably collinear covariates or intermediate variables, i.e., a large lesion may cause the baseline GFR to be lower, which would, in turn, cause the GFR at 6 months to be lower. Our findings resonate with those of Urabe et al (22) , who showed that the percent decline in GFR on postoperative day 1 was the only independent predictor of GFR at 6 months after percutaneous cryoablation of renal tumors. Some of the variables we evaluated as predictors of post-cryoablation renal function are in keeping with those previously evaluated in the literature.…”

“…For example, Zhou et al (21) found CT-guided percutaneous microwave ablation to be a safe procedure, post-ablation imaging showing a complete response in 42 (95%) of the 44 tumors ablated and renal function remaining stable at 1 month after ablation. In addition, Urabe et al (22) found that, among patients undergoing cryoablation, the decline in renal function at 6 months after the procedure was comparable between those with CKD and those without. Those authors found that renal function was significantly impaired in the early post-cryoablation period and did not recover in the 6 months thereafter.…”

Editorial Comment from Dr Hongo to Estimated glomerular filtration rate on postoperative day 1 is associated with renal functional outcome after percutaneous renal cryoablation for renal tumors

“…Urabe et al . showed that the estimated glomerular filtration rate on postoperative day 1 predicts renal functional outcome …”

Editorial Comment from Dr Teishima and Dr Matsubara to Estimated glomerular filtration rate on postoperative day 1 is associated with renal functional outcome after percutaneous renal cryoablation for renal tumors

“…Urabe et al . reported on the impact of using the estimated glomerular filtration rate on postoperative day 1 on predicting renal functional outcomes after percutaneous renal cryoablation for small renal masses (SRMs) . Recently, there have been various therapeutic modalities for SRMs including partial nephrectomy (PN), percutaneous cryoablation (PCA), radiofrequency ablation and active surveillance.…”