. 2005. Lipogenic activity in Rasa Aragonesa ewes of different body condition score. Can. J. Anim. Sci. 85: 101-105. The aim of the study was to assess the effect of body condition score on tissue and metabolic characteristics of the adipose depots in sheep of Rasa Aragonesa breed. Ewes were uniformly assigned according to their body condition score (BCS) (scale 0 to 5), to four groups: 0.75-1.75, 2-2.75, 3-3.75, and 4-4.5. The amount of fat and the adipocyte size in the different adipose depots increased as BCS did (P < 0.001) while the number of adipocytes did not change. The greatest ability to accumulate or mobilize fat was the subcutaneous depot (slope of the regression between amount of fat and BCS, b = 1.92; P < 0.001). Fatty acid synthase (FAS) lipogenic enzyme activity was affected by BCS, while G3-PDH and G6-PDH activities were not.Key words: Adipose tissue, body condition score, adipocyte size, lipogenic enzyme activity, ewes Arana, A., Mendizabal, J. A., Delfa, R., Eguinoa, P., Soret, B., Alzon, M. et Purroy, A. 2005. Activité lipogénique des brebis Rasa Aragonesa avec différent note d'état corporel. Can. J. Anim. Sci. 85: 101-105. On a etudié l'effet de la note d'état corporel (nCC) sur le metabolisme des differentes dépots adipeux dans les brebis de race Rasa Aragonesa, distribuées dans quatre groups de nCC (échelle 0-5): 0,75-1,75, 2-2,75, 3-3,75, et 4-4,5. La quantité de tissu adipeux et le diamètre des adipocytes des differentes dépots ont augmenté avec la nCC des brebis (P < 0,001) mais il n'a pas eu de variation du nombre des adipocytes. Le tissu adipeux sous-cutané a montré la plus grande capacité d'acumulation/mobilisation (pente de la regression entre la quantité de tissu adipeux et la nCC, b = 1,92; P < 0,001). En ce qui concerne à l'activité des enzymes lipogéniques, uniquement on a trouvé variation de l'activité de l'enzyme FAS Mots clés: Tissu adipeux, note d'état corporel, taille des adipocytes, activité enzymatique lipogénique, brebis Sheep accumulate fat reserves when feed is available in excess and mobilize it when feed is limiting. Fat mobilization occurs mainly over the first period of lactation and the total loss of fat reserves can reach 70% (Cowan et al. 1979). Depending on the production system used, recovery of fat reserves is initiated either after weaning or during the final stage of lactation. Fat accumulation will then take place until mating or even during early gestation. The activity of different lipogenic and lipolytic enzymes is involved in the fat accumulation and mobilization processes. Furthermore, there are changes in adipose tissue cellularity, mainly in adipocyte size, which are achieved by changes in enzyme activity (Vernon 1986).There are different studies of adipose tissue metabolism in sheep either in periods of negative energy balance when fat mobilization occurs (Vernon et al. 1981) or in periods of positive energy balance when fat accretion exists (Sebastian et al. 1993). Nevertheless, the body condition score (range from 0 to 5; Russel et al. 1969) of t...