Estimation of Reference Values for External Genitalia Parameters in North Indian Preterm and Term Female Newborns

Normative Data for External Genitalia Parameters in Female Newborns

“…In fact, previous studies also indicate that the conventional cut-off of 10 mm to define clitoromegaly may have been an overestimation of clitoral size due to erroneous inclusion of the clitoral hood instead of the clitoral glans during measurement [7]. In the present study, the AGR was found to be similar in all gestations and a cut-off value more than 0.45 is suggested to indicate in utero androgen exposure [5]. The study by Nanda et al provides useful normative data for neonatologists and pediatric endocrinologists to apply in evaluation of newborns with suspected virilization.…”

“…In this issue of the Journal, Nanda et al report the gestation-wise percentile charts on clitoral size and AGR in a large cohort of term and preterm female newborns (n = 508) from North India using standardized methods of measurement [5]. Previously, Mondal et al have reported normative data of term and preterm female newborns from the Eastern part of India [6].…”

When to address form and when to address function: Timing of surgical reconstruction for a patient with 46 XY DSD

“…The patient was seen on day 3 of life by a pediatric endocrinologist for “ambiguous genitalia.” Physical exam demonstrated thick labia majora, a phallic structure length measurement of 0.8 cm (normal 4.6 ± 1.8 mm). 3 The urethra was noted on the underside of the phallic structure and no gonads were palpated. Pelvic ultrasound failed to reveal a uterus or ovaries but showed possible gonads in the inguinal canals ( Fig.…”