Estimation of Serum Beta 2- microglobulin among newly diagnosed children with cancer in Basra

Abstract

How to cite this article: Aziz AM, Hasan JG. Estimation of Serum Beta 2-microglobulin among newly diagnosed children with cancer in Basra. J Radiol Oncol. 2018; 2: 022-035. https://doi.org/10.29328/journal.jro.1001018 IntroductionAlthough childhood cancer is rare, accounting for less than 1 per cent of all cancer in industrialized countries, it is of great scienti ic interest for a number of reasons. Several types of cancer are actually unique to childhood, whereas the carcinomas most frequently seen in adults, those of lung, female breast, stomach, large bowel, and prostate, are extremely rare among children [1]. Beta 2-microglobulin (β2-MG) is involved in cancer and other human malignancies. Increased synthesis and release of β2-MG , as indicated by elevated serum, plasma, or urine β2-MG concentration, occurs in several malignant diseases, including prostate cancer, lung cancer, breast cancer, renal cell carcinoma (RCC), gastrointestinal and nasopharyngeal cancers, hepatocellular Abstract Background: Beta 2-micro globulin (β2-MG) is involved in human malignancies. Increased synthesis and release of β2-MG, as indicated by elevated serum, plasma, or urine β2-MG concentration, occurs in several malignant diseases,