Objectives: To predict body height using hand length and hand breadth in pharmacy and nursing students at Misrake Ghion College, Northeast Ethiopia. Methods: A cross-sectional prospective study was conducted from October 15 to January 20, 2021. The study was carried out on 316 students (160 males and 156 females). The study participants were from the Amhara ethnic groups, with the age range of 18 to 25 years. Body height, hand length, and hand breath were measured and analyzed using SPSS version 23. The strength of association was evaluated using correlation analysis. The significance level was set at p < 0.05. A paired sample t test was performed. Regression equations were derived using simple and multiple linear regression analysis. Results: Hand length and hand breadth had a positive significant correlation with body height in both male and females. In both males and females, left hand length had a strong significant correlation (males r = 0.768, females r = 0.670), followed by right hand length (males r = 0.711, females r = 0.626). Regarding hand length, right hand breadth (males r = 0.671, female r = 0.438) and left hand length (males r = 0.504, females r = 0.525). There was a significant bilateral difference in hand length and hand breadth on its right and left sides ( p < 0.05). Simple and multiple regression equations were formulated for each sex. Conclusion: In both males and females, body height can be estimated from hand length and breadth using simple or multiple regression equations.