1939
DOI: 10.1016/s0140-6736(00)79960-0
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Estimation of Sulphanilamide in Biological Fluids

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Cited by 45 publications
(6 citation statements)
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“…In such an acute disease as pneumonia it may be advisable in severe cases to control the level of blood sulphapyridine by chemical estimation. The method described by Werner (1939) is an admirable one for clinical purposes. Using this method, I found that adequate blood levels of the drug could be maintained in the average case by giving the following dosage: These findings closely agree with the dosage worked out by Hynes (1940) at the Hospital for Sick Children, Great Ormond Street.…”
Section: Methods Of Therapy In Infantile Pneumoniamentioning
confidence: 99%
“…In such an acute disease as pneumonia it may be advisable in severe cases to control the level of blood sulphapyridine by chemical estimation. The method described by Werner (1939) is an admirable one for clinical purposes. Using this method, I found that adequate blood levels of the drug could be maintained in the average case by giving the following dosage: These findings closely agree with the dosage worked out by Hynes (1940) at the Hospital for Sick Children, Great Ormond Street.…”
Section: Methods Of Therapy In Infantile Pneumoniamentioning
confidence: 99%
“…The method of Werner (1939) was adapted for continuous automatic sampling and assay using the Autoanalyser. This is shown diagrammatically in Fig.…”
Section: Hlethod Of Analysismentioning
confidence: 99%
“…The method isas mentioneda modification ui the method of Werner (1939) for the determination of sulplionamides. The improvements in this method introduced by Morris (1941) using ptoluenesulphonic acid as protein precipitating reagent and an alcoholic solution of dimethylaminobenzaldehyd have been adopted.…”
Section: Principlementioning
confidence: 99%