Ethics: China already has clear stem-cell guidelines

Cheng, Linzhao; Qiu, Ren Zong; Deng, Hongkui; Zhang, Yu Alex; Jin, Ying; Li, Lingsong

doi:10.1038/440992b

Cited by 16 publications

(12 citation statements)

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“…Interviewees stated that enforcement of regulations are a key concern: "We do not have the mature process to examine, so we're not really sure if [the regulations] were implemented totally or not…it is difficult to know whether the policy has been carried out completely because we do not have the examination to really verify". Some of the top stem cell researchers in China have stated that despite this, they consider the stem cell guidelines to be adequate and binding [19]. One interviewee stated "Right now the regulation is, I think it's fine.…”

Section: Regulatory Concernsmentioning

confidence: 99%

Cultivating Regenerative Medicine Innovation in China

et al. 2010

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Section: Regulatory Concernsmentioning

confidence: 99%

Cultivating Regenerative Medicine Innovation in China

et al. 2010

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“…All hESC experiments were conducted in accordance with the guidelines for research on hESCs, jointly issued by the Ministry of Science and Technology and the Ministry of Health of China [27], and approved by the ethical committee of Fourth Military Medical University (National Natural Science Foundation of China No. 30800928, 09/01/2009).…”

Section: Methodsmentioning

confidence: 99%

Effects of Pulsed Electromagnetic Field on Differentiation of HUES-17 Human Embryonic Stem Cell Line

Peng

et al. 2014

IJMS

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Electromagnetic fields are considered to potentially affect embryonic development, but the mechanism is still unknown. In this study, human embryonic stem cell (hESC) line HUES-17 was applied to explore the mechanism of exposure on embryonic development to pulsed electromagnetic field (PEMF) for 400 pulses at different electric field intensities and the differentiation of HUES-17 cells was observed after PEMF exposure. The expression of alkaline phosphatase (AP), stage-specific embryonic antigen-3 (SSEA-3), SSEA-4 and the mRNA level and protein level of Oct4, Sox2 and Nanog in HUES-17 cells remained unchanged after PEMF exposure at the electric field intensities of 50, 100, 200 or 400 kV/m. Four hundred pulses PEMF exposure at the electric field intensities of 50, 100, 200 or 400 kV/m did not affect the differentiation of HUES-17 cells. The reason why electromagnetic fields affect embryonic development may be due to other mechanisms rather than affecting the differentiation of embryonic stem cells.

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“…Later that year they also issued Ethical Guidelines for Research on Human Embryonic Stem Cells. Both sets of guidelines banned human reproductive cloning (Cheng, 2006). In an increasingly globalized scientific world, however, pressures from international ethical surveillance and critique often overrode autonomous self-reflection and became the driving force pushing China's ethical regulations.…”

Section: Finding Contextsmentioning

confidence: 99%