Ethyl 2-acetyl-3-anilinobutanoate

Priya, S.; Sinha, Sitabhra; Vijayakumar, V.; Narasimhamurthy, T.; Vijay, T.; Rathore, R. S.

doi:10.1107/s1600536806044588

Cited by 3 publications

(4 citation statements)

References 3 publications

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“…Our group reported the catalyst‐free synthesis of alkyl 2‐acetyl‐3‐(phenylamino)butanoates using arylamines, acetaldehyde and β‐ketoesters [19–21] . The amine and acetaldehyde initially react to give an imine, which in turn reacts with a β‐ketoester through a Michael addition.…”

Section: Resultsmentioning

confidence: 99%

Montmorillonite K10 Clay Catalyzed Synthesis of Novel β‐Aminocarbonyl Compounds and Their Biological Evaluation

Rambabu

Kiran²,

Tarakeswar³

et al. 2022

Chemistry & Biodiversity

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An efficient and reusable green catalyst for the synthesis of β-aminocarbonyl compounds has been developed. In this new and greener approach, β-aminocarbonyl compounds (1a -1r) were obtained by Montmorillonite K10 clay catalyzed reaction of aryl amines, aliphatic/aromatic aldehydes and β-ketoesters. Molecular docking investigations were performed for all compounds (1a -1r) with the proteins PDB ID: 1JIJ and 1KZN for S. aureus and E. coli, respectively. For all compounds good to strong interactions with the active sites were observed. The biological activities of β-aminocarbonyl compounds were further assessed for their antibacterial and antioxidant activities. The results confirmed that β-aminocarbonyl compounds could be further developed into new drugs with potent antibacterial and antioxidant activities.

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Section: Resultsmentioning

confidence: 99%

Montmorillonite K10 Clay Catalyzed Synthesis of Novel β‐Aminocarbonyl Compounds and Their Biological Evaluation

Rambabu

Kiran²,

Tarakeswar³

et al. 2022

Chemistry & Biodiversity

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“…For related structures see: Rajesh et al (2009); Priya et al (2006). For hydrogen-bond motifs, see: Bernstein et al (1995).…”

Section: Related Literaturementioning

confidence: 99%

Ethyl 2-acetyl-3-(4-bromoanilino)butanoate

Reddy

Vijayakumar

Suresh³

et al. 2010

Acta Cryst E

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“…For the crystal structure of ethyl 2-acetyl-3-anilinobutanoate, see: Priya et al (2006). For hydrogen-bond motifs, see: Bernstein et al (1995).…”

Section: Related Literaturementioning

confidence: 99%

“…Ethyl butanoate is commonly used as an artificial flavoring agent in alcoholic beverages, perfumery products and as a plasticizer for cellulose. The crystal structure of ethyl 2-acetyl-3-anilinobutanoate has been reported (Priya et al, 2006).…”

Section: Data Collectionmentioning

confidence: 99%