Ethylene glycol dimethacrylate modified hyper-cross-linked resins: Porogen effect on pore structure and adsorption performance

Preparation of Ethylene Glycol Dimethacrylate (EGDMA)-Based Terpolymer as Potential Sorbents for Pharmaceuticals Adsorption

“…Hence, in the case of porosity analysis, we may conclude that low specific surface area of HP7 was due to the chemical reactions during hypercrosslinking that disrupted the wall of the pores and thus resulted to high mean pore size (447 nm). The presence of a stabilizer such as polyvinyl alcohol (PVA) or poly(N-vinylpyrrolidone) (PVP) in synthesizing EGDMA-based polymer plays a big role in producing well-defined spherical particles (beads) [24,44] with high porosity polymer microspheres [16,18]. The stabilizers hinder the coalescence of monomer droplets and then stabilize the polymer beads that have a tendency to agglomerate [45].…”

“…In recent years, hypercrosslinked polymers have been attracting increasing attention in the field of adsorption due to their high Brunauer-Emmett-Teller (BET) surface area (1000 m 2 •g −1 ) and a large number of micropores [9][10][11][12][13][14][15][16][17][18][19][20][21][22]. It has been reported that high maximum adsorption capacity of salicylic acid was obtained (up to 621 mg•g −1 ) by utilizing the hypercrosslinked resins as the adsorbents [15,19,20].…”

“…Yu and his team reported the adsorption of p-aminobenzoic acid (pharmaceutical intermediates) by modified hypercrosslinked chloromethylated styrene/divinylbenzene with the maximum adsorption capacity of 300 mg•g −1 [23]. Zhang et al [16] and Wang et al [18] introduced ethylene glycol dimethacrylate (EGDMA) as a polar crosslinking agent and vinylbenzyl chloride (VBC), where the chloromethyl (-CH 2 Cl) substituent acts as an internal electrophile in preparing hypercrosslinked polymers. The synthesis of hypercrosslinked polymers by Friedel-Crafts reactions involved the conversion of chloromethyl group into methylene bridge where chlorine atom utilized as a leaving group to form methylene bridges between adjacent phenyl rings and therefore, lead to the formation of abundant pores inside the precursor polymer [24][25][26][27][28][29].…”

“…The synthesis of hypercrosslinked polymers by Friedel-Crafts reactions involved the conversion of chloromethyl group into methylene bridge where chlorine atom utilized as a leaving group to form methylene bridges between adjacent phenyl rings and therefore, lead to the formation of abundant pores inside the precursor polymer [24][25][26][27][28][29]. It was reported that incorporation of 90% of VBC in the feed (in poly(EGDMA-co-VBC) system) resulted in the formation of hypercrosslinked particles with high porosity; 1066 m 2 •g −1 [18] and 827 m 2 •g −1 [16]. Hypercrosslinked polymer composed of acrylonitrile (AN) as the polar monomer, divinylbenzene (DVB) as a crosslinker and VBC was reported by Subri et al [14].…”

Novel CaO/polylactic acid nanoscaffold as dental resin nanocomposites and the investigation of physicochemical properties

“…The use of nanocomposite resins improves the bond between the tooth structure and the restorative materials, which leads to a more stable and natural interface . Previous studies indicate that the use of many kinds of materials for composite resins such as acrylic resins, silicate cements, matrix organic phases as dimethacrylate, urethane dimethacrylate (UDMA), triethyleneglycol dimethacrylate (TEGDMA), bisphenol‐A‐dimethacrylate (Bis‐EMA), decanediol dimethacrylate (D 3 MA) raises concerns about the mechanical and fracture properties owing to the large size of the particles. Recently, micelles have been shown significant interest and attention as delivery systems for poorly water‐soluble drugs.…”