Etiologic and Cardiovascular Risk Factors in Obese Children From Extremadura in Spain. Their Relationship With Insulin Resistance and Plasma Adipocytokine Levels

Torres, M.D.; Tormo, María Ángeles; Campillo, Carlos; Carmona, M.; Torres, María Teresa Marín; Reymundo, M. García; García, Purificación Cremades; Campillo, J. E.

doi:10.1016/s1885-5857(08)60252-2

Cited by 3 publications

(3 citation statements)

References 40 publications

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“…65 Consequently, these changes may occur in the early stages of the pathological process of atherosclerosis, leading to the gradual development of cardiovascular diseases. 65 The qualitative analysis of the studies showed that sedentary behavior, indicated primarily by prolonged exposure to screen time, was frequently associated with higher adiposity indices, 13,28,31,38,[45][46][47]49,52 elevated BP, 15,25,52,55 low values of HDL cholesterol, 25,28,31 elevated levels of serum insulin 16 and insulin resistance, 16,23 increased risk of metabolic syndrome 1,7,25 and higher CR. 43 When TV time was analyzed individually as an indicator of sedentary behavior, the results showed that prolonged time spent watching TV was associated with increased body adiposity, 11,14,20,22,26,28,33,35,39,43,47,48,51 elevated SBP 14,15,37,43,47,48 and DBP, 14,15,37,38…”

Section: Discussionmentioning

confidence: 99%

“…Regarding the type of sedentary activity, prolonged screen time was frequently associated with increased BMI, 13,28,38,45,47,52 WC, 28,31,38,45 waist-to-height ratio (WHR), 38 and skin-fold thickness. 46 Moreover, TV time assessed individually was positively associated with BMI, 14,28,33,35,47 WC, 22,26,28,35,39,43,47 WHR, 26,48 and BF.…”

Section: Sedentary Behavior and Body Adipositymentioning

confidence: 99%

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Sedentary Behavior and Cardiovascular Risk in Children: A Systematic Review

Canabrava

Amorim

Miranda

et al. 2019

Rev Bras Med Esporte

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In recognition of the increasing time spent in sedentary activities in modern life, an emerging area of study linking sedentary time to health has highlighted its role in the development of chronic diseases. Therefore, the objective of this systematic review was to investigate the indicators and characteristics of sedentary behavior associated with cardiovascular risk factors in children and adolescents. The databases SciVerse Scopus, MEDLINE®/PubMed and LILACS were selected as a source of reference, using the associated terms “sedentary lifestyle” or “sedentary behavior” or “sedentary” AND “cardiovascular diseases” AND “child or adolescent” to identify studies published from January 2006 to March 2019. The methodological quality of the studies was evaluated and a score was assigned. Fifty articles were included in this review at the end. Extensive sedentary time, especially greater screen and TV exposure time, were associated with cardiovascular risk factors. In addition, the accumulation of prolonged sedentary bouts with few breaks in sedentary time tended to compromise the cardiometabolic profile. These findings highlight the importance of differentiating and considering these various indicators and characteristics of sedentary behavior. Further studies are needed to elucidate the multiple and overlapping facets of sedentary behavior and their relationship with health, and to encourage the development of evidence-based recommendations for this population. Level of Evidence I; Systematic Review of Level I Studies.

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Section: Discussionmentioning

confidence: 99%

Section: Sedentary Behavior and Body Adipositymentioning

confidence: 99%

Sedentary Behavior and Cardiovascular Risk in Children: A Systematic Review

Canabrava

Amorim

Miranda

et al. 2019

Rev Bras Med Esporte

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“…En sujetos de edad pediátrica, se ha reportado diferencia significativa entre eutróficos y obesos [11][12][13][19][20][21][22] y se ha encontrado correlación positiva entre resistina e IMC 9,19,21 , relación que es considerada por algunos autores como fuerte e independiente de la edad, género y estadio puberal, en obesos 22 . Por el contrario, se ha reportado que no existe diferencia significativa en los niveles de resistina entre eutróficos y obesos 1,3,5,9,23,[24][25][26] o correlación entre ambas variables 1,23,25,27 .…”

Section: Discussionunclassified

Asociación de la resistina con variables de dimensión y composición corporal en eutróficos y obesos

et al. 2016

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Body Composition Differences in Normal Weight, Obese-Overweight and Anorexic Adolescents: Role of Adipocytokines

Ondrak¹,

Hackney²

2010

Medicine and Sport Science

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Adipocytokines are signaling molecules released by adipose tissue with numerous functions, including regulation of metabolism, inflammatory process, and body mass. They are particularly interesting in youth, considering the rising prevalence of overweight/obesity and the linkage of this condition to inflammation. This chapter examines the relationship between body composition and select adipocytokines: leptin, adiponectin, IL-6, TNF-α, and resistin, in overweight, normal weight and anorexic youth. Leptin, which stimulates energy expenditure and promotes satiety, is highest in overweight youth, followed by normal weight and lastly anorexic youth. Adiponectin has similar functions to leptin but is negatively correlated with measures of body composition. Anorexic youth have the highest adiponectin per kg fat mass, followed by normal weight and overweight. Conversely, IL-6 is positively associated with body composition; however, research in anorexic youth is inconclusive. It has some pro-inflammatory effects and promotes glucose and fat use, therefore beneficial for maintenance of normal weight status. TNF-α is also a pro-inflammatory adipocytokine thought to be somewhat protective against cancer. TNF-α is highest in overweight, followed by normal weight and anorexic youth, similar to leptin. Finally, resistin is also involved in the pro-inflammatory response and the development of insulin resistance. However, far less research exists on this adipocytokine and its relation to body composition in overweight or anorexic youth is equivocal. In conclusion, several consistent relationships exist regarding adipocytokines and body composition; however, there is a need for additional research on these relationships in youth especially at extremes of adiposity such as overweight and anorexics.

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Etiologic and Cardiovascular Risk Factors in Obese Children From Extremadura in Spain. Their Relationship With Insulin Resistance and Plasma Adipocytokine Levels

Cited by 3 publications

References 40 publications

Sedentary Behavior and Cardiovascular Risk in Children: A Systematic Review

Sedentary Behavior and Cardiovascular Risk in Children: A Systematic Review

Asociación de la resistina con variables de dimensión y composición corporal en eutróficos y obesos

Body Composition Differences in Normal Weight, Obese-Overweight and Anorexic Adolescents: Role of Adipocytokines

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