Etiologic Factors in Ulcerative Colitis: Birth, Death and Symbolic Equivalents

Paull, A.; Hislop, I. G.

doi:10.2190/kbck-2xjt-uwht-7c6a

Cited by 13 publications

(5 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There have been many studies in IBD documenting an association between the onset of IBD with recent stressful life events and suggested any perceived psychological distress even not related to disease activity can also influence the course of the disease [ 65 , 284 , 285 ]. Such studies also examined the effects by the disease on patients’ psychological state.…”

Section: Inflammatory Bowel Diseasesmentioning

confidence: 99%

A Review of Inflammatory Bowel Disease: A Model of Microbial, Immune and Neuropsychological Integration

et al. 2021

View full text Add to dashboard Cite

Objective: Inflammatory bowel diseases (IBDs) are complex chronic inflammatory disorders of the gastro-intestinal (GI) tract with uncertain etiology. IBDs comprise two idiopathic disorders: Crohn’s disease (CD) and ulcerative colitis (UC). The aetiology, severity and progression of such disorders are still poorly understood but thought to be influenced by multiple factors (including genetic, environmental, immunological, physiological, psychological factors and gut microbiome) and their interactions. The overarching aim of this review is to evaluate the extent and nature of the interrelationship between these factors with the disease course. A broader conceptual and longitudinal framework of possible neuro-visceral integration, core microbiome analysis and immune modulation assessment may be useful in accurately documenting and characterizing the nature and temporal continuity of crosstalk between these factors and the role of their interaction (s) in IBD disease activity. Characterization of these interactions holds the promise of identifying novel diagnostic, interventions, and therapeutic strategies.Material and Methods: A search of published literature was conducted by exploring PubMed, EMBASE, MEDLINE, Medline Plus, CDSR library databases. Following search terms relating to key question were set for the search included: “Inflammatory bowel diseases,” “gut microbiota,” “psychological distress and IBD,” “autonomic reactivity and IBD,” “immune modulation,” “chronic inflammation,” “gut inflammation,” “enteric nervous system,” “gut nervous system,” “Crohn’s disease,” “Ulcerative colitis”, “depression and IBD”, “anxiety and IBD”, “quality of life in IBD patients,” “relapse in IBDs,” “remission in IBDs,” “IBD disease activity,” “brain-gut-axis,” “microbial signature in IBD,” “validated questionnaires in IBD,” “IBD activity indices,” “IBD aetiology,” “IBDs and stress,” “epidemiology of IBDs”, “autonomic nervous system and gut inflammation”, “IBD and environment,” “genetics of IBDs,” “pathways of immune response in IBDs,” “sleep disturbances in IBD,” “hypothalamic-pituitary-adrenal axis (HPA),” “sympatho-adrenal axis,” “CNS and its control of gut function” “mucosal immune response,” “commensal and pathogenic bacteria in the gut,” “innate and adaptive immunity.” Studies evaluating any possible associations between gut microbiome, psychological state, immune modulation, and autonomic function with IBDs were identified. Commonly cited published literatures with high quality research methodology/results and additional articles from bibliographies of recovered papers were examined and included where relevant.Results: Although there is a substantial literature identifying major contributing factors with IBD, there has been little attempt to integrate some factors over time and assess their interplay and relationship with IBD disease activity. Such contributing factors include genetic and environmental factors, gut microbiota composition and function, physiological factors, psychological state and gut immune response. Interdependences are evident across psychological and biological factors and IBD disease activity. Although from the available evidence, it is implausible that a single explanatory model could elucidate the interplay between such factors and the disease course as well as the sequence of the effect during the pathophysiology of IBD.Conclusion: Longitudinal monitoring of IBD patients and integrating data related to the contributing/risk factors including psychological state, physiological conditions, inflammatory/immune modulations, and microbiome composition/function, could help to explain how major factors associate and interrelate leading to exacerbation of symptoms and disease activity. Identifying the temporal trajectory of biological and psychosocial disturbances may also help to assess their effects and interdependence on individuals’ disease status. Moreover, this allows greater insight into understanding the temporal progressions of subclinical events as potential ground for disease severity in IBD. Furthermore, understanding the interaction between these risk factors may help better interventions in controlling the disease, reducing the costs related to disease management, further implications for clinical practice and research approaches in addition to improving patients’ mental health and quality of life.

show abstract

Section: Inflammatory Bowel Diseasesmentioning

confidence: 99%

A Review of Inflammatory Bowel Disease: A Model of Microbial, Immune and Neuropsychological Integration

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Evidence for the impact of either a "premorbid pessimistic" attitude or an outlook of "future despair" on physical disease seems well established. This constellation is in no way illness specific, however; there are studies showing its relationship to a wide variety of diseases such as multiple sclerosis, ulcerative colitis, and cancer (Mei-Tal, Meyerowitz, & Engel, 1970;Paull & Hislop, 1974;Schmale, 1972). This depressive pattern has also been researched in relation to postoperative course; a good surgical outcome seems to be correlated with an acceptance of one's health problems and a positive, future-oriented attitude (Boyd, Yeager, & McMillan, 1973).…”

Section: Search For Relevant Personological and Psychogenic Health Di...mentioning

confidence: 99%

A new psychodiagnostic tool for clients in rehabilitation settings: The MBHI.

Millon¹,

Green²,

Meagher³

1982

Rehabilitation Psychology

View full text Add to dashboard Cite

There are very few psychodiagnostic instruments for assessing the emotional stability, cognitive outlook, and coping style of clients seen in rehabilitation settings. Established clinical tools have been designed for psychiatric populations and are only tangentially relevant. Excellent recent instruments for rehabilitation populations tend to focus on overt behavioral indices or vocational aptitudes. To supplement these latter realms of functioning, the Millon Behavioral Health Inventory (MBHI), a 150-item self-report inventory, may be seen to provide measures relevant to the client's psychological outlook and prognosis. It also appears useful as a guide for treatment planning and psychological counseling. The rationale, development, and uses of the MBHI are briefly described, while the focus of each of the instrument's 20 scales is also outlined.The client with rehabilitation needs may enter the health care system with a physical, functional, and/or psychological problem. Although medically stabilized, at least in regard to life-threatening concerns such as postsurgical complications, the client is now beginning a long, arduous, and highly individualized recovery process. Clinical health psychologists (Millon, Green, & Meagher, in press) play a central role in all phases of this process-from diagnosis, to treatment planning, to direct work with the client in facilitating recovery.The responsibilities of this multifaceted role neither require that the psychologist discard familiar clinical skills or techniques nor transform himself or herself into a totally new professional. However, they do call for the use of assessment and treatment tools that are more relevant to rehabilitation populations than those in the standard clinical armamentarium. The psychologist should seek creatively to extend previously acquired competencies to fit these new responsibilities. One such skill, that of psychodiagnostic assessment in rehabilitation settings, is the focus of this article. Fulfilling the role of psychodiagnostician in this setting may require considerable ingenuity and flexibility, since the task calls for tools, concepts, and strategies other than those that psychologists are likely to have been trained to employ in conventional mental health settings.

show abstract

“…Evidence for the impact of either a premorbidpessimistic attitude or an outlook of future despair on physical disease seems well established. This constellation is in no way illness specific, however, since there are studies showing its relationship to a wide variety of diseases such as multiple sclerosis, ulcerative colitis, and cancer (Mei-Tal, Meyerowitz, & Engel, 1970;Paull & Hislop, 1974;Schmale, 1972). This depressive pattern has also been researched in relation to postoperative course; a good surgical outcome seems to be correlated with an acceptance of one's health problems and a positive, future-oriented attitude (Boyd, Yeager, & McMillan, 1973).…”

Section: Search For Relevant Behavioral Health Dimensionsmentioning

confidence: 99%

The MBHI: A new inventory for the psychodiagnostician in medical settings.

Millon¹,

Green²,

Meagher³

1979

Professional Psychology

View full text Add to dashboard Cite

where he directed the behavioral sciences teaching program and edited the associated text, Medical Behavioral Science, now used at numerous medical schools. A member of the DSM-111 Task Force, his primary work has been in clinical research. Among his books are Modern Psychopathology, Theories of Psychopathology, and Research Methods in Psychopathology. CATHERINE GREEN is a recent PhD from Loyola University of Chicago. Her primary work has been in health research and the clinical counseling of the physically ill.

show abstract

Etiologic Factors in Ulcerative Colitis: Birth, Death and Symbolic Equivalents

Cited by 13 publications

References 20 publications

A Review of Inflammatory Bowel Disease: A Model of Microbial, Immune and Neuropsychological Integration

A Review of Inflammatory Bowel Disease: A Model of Microbial, Immune and Neuropsychological Integration

A new psychodiagnostic tool for clients in rehabilitation settings: The MBHI.

The MBHI: A new inventory for the psychodiagnostician in medical settings.

Contact Info

Product

Resources

About