Etoricoxib- induced pleural effusion: A case for rational use of analgesics

Abstract

Pleural effusion caused by drug is an uncommon event in clinical practice. Etoricoxib induced pleural effusion is an extremely rare. We describe a patient with pleural effusion as an adverse drug reaction of etoricoxib.

Etoricoxib‐induced pleural effusion: A case report

“…3 When looking at etoricoxib's side effects, it is clear that the drug rarely causes pleural effusion, and there are only a few published case reports. 2 The onset of dyspnea in our patient coincides with the start of etoricoxib therapy, with no additional etiologies identified by a thorough study that ruled out all common illnesses, strengthening our conclusion. As shown in our patient, the symptoms could be severe enough to produce severe dyspnea and necessitate hospitalization.…”

“…Etoricoxib is contraindicated in people with uncontrolled hypertension, ischemic heart disease, or stroke, and it should be used with caution in patients with heart disease risk factors, according to the European Medicines Agency 3 . When looking at etoricoxib's side effects, it is clear that the drug rarely causes pleural effusion, and there are only a few published case reports 2 …”

“…Warfarin, diltiazem, simvastatin, imidapril, propylthiouracil, and mesalamine are among the medications in the first group, which are extremely heterogeneous. 2 Nitrofurantoin, daptomycin, and tosufloxacin are among the chemotherapeutics and antibiotics in the second group. Etoricoxib, a selective COX-2 inhibitor, has recently been found to cause pleural effusion.…”

“…There are two types of drugs linked to pleural effusion. Warfarin, diltiazem, simvastatin, imidapril, propylthiouracil, and mesalamine are among the medications in the first group, which are extremely heterogeneous 2 . Nitrofurantoin, daptomycin, and tosufloxacin are among the chemotherapeutics and antibiotics in the second group.…”

Etoricoxib Induced Skin Rashes: Case Report

“…1,2,3 Although it is highly efficacious in pain management, the safety profile of COX-2 inhibitor is yet not established in a broader sense. 4,5 The drug is approved in more than 80 countries but not in US because the FDA has asked for additional data for proving safety and efficacy before issuing its approval.…”