EUS-guided, fine-needle aspiration biopsy using a new mechanical scanning puncture echoendoscope

Utility of pancreatic duct brushing for diagnosis of pancreatic carcinoma

“…[2][3][4][5][6] However, its availability is limited because equipment for EUS-guided FNA is expensive and the technique is relatively diffi cult. Harewood and Wiersema 9 reported that the sensitivity of EUS-guided FNA is satisfactory even in patients negative for computed tomographyguided biopsy or ERCP tissue sampling.…”

“…1 The sensitivity of EUS-guided FNA for malignancy of the pancreas has been reported to range from 84.3% to 95%. [2][3][4][5][6] Endoscopic pancreatic duct brushing is a convenient method for the defi nitive diagnosis of pancreatic masses. However, the sensitivity of pancreatic duct brushing is recognized to be generally low compared with that of EUS-guided FNA.…”

Needle-based confocal endomicroscopy for in vivo histology of intra-abdominal organs: first results in a porcine model (with )

“…Suspicious lesions, inflammation, or neoplasia are differentiated by morphologic alterations or according to the results of EUSguided core needle biopsies or FNA. However, EUSguided biopsies or aspirations fail in up to 10% of cases owing to quality of the aquired specimen 15 and are of incongruent diagnostic accuracy in detecting malignancy. 16 Because of the increased number of biopsies and the immediate evaluation of the acquired "virtual biopsies," nCLE might result in a higher diagnostic yield when used as a guidance for standard EUS-guided samples and might also provide diagnosis within the same procedure.…”

Feasibility and preliminary accuracy of high-resolution imaging of the liver and pancreas using FNA compatible microendoscopy (with video)

“…In early studies, EUS-FNA was found to be equal or superior to other imaging modalities including CT and MRI for assessing tumor size and lymph node involvement 1 . However, EUS-FNA has been shown to have a failure rate of up to 10% due to poor specimen quality, sampling error, and its inability to distinguish confounders such as acute and chronic pancreatitis 2-5 .…”