Evaluating Anisotropic Properties in the Porcine Temporomandibular Joint Disc Using Nanoindentation

Yuya, Philip A.; Amborn, E. K.; Beatty, Mark W.; Turner, Joseph A.

doi:10.1007/s10439-010-9967-8

Cited by 19 publications

(14 citation statements)

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“…Nanoindentation is attractive because measurements are uniquely capable of characterizing the mechanical response of bone at the submicrostructural level, thus providing mechanical properties of individual bone constituents. Measurements have high spatial resolution due to small indenter tip radius, are nondestructive on a macroscopic level, and are sensitive to material anisotropy [32][33][34][35]. The understanding of measurement limitations and complexities has grown as the technique has been applied to bone.…”

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confidence: 99%

Intrinsic Material Properties of Trabecular Bone by Nanoindentation Testing of Biopsies Taken from Healthy Women Before and After Menopause

et al. 2012

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Postmenopausal osteoporosis in women is characterized by an increase in bone fragility and risk of fracture. In addition to transmenopausal decline in three-dimensional trabecular bone architecture, changes in intrinsic material properties (local stiffness, damping, and hardness) may contribute to increased bone fragility. In this study, nanoindentation was used to quantify transmenopausal changes in the intrinsic properties of trabecular bone. Paired transilial biopsy specimens were used from a previously reported study in which bone biopsies were obtained from women prior to menopause (premenopausal, age 49.0 ± 1.9) and at 12 months past the last menstrual period (postmenopausal, age 54.6 ± 2.2). Elastic and viscoelastic material properties of the trabecular bone were measured using quasi-static and dynamic nanoindentation techniques, respectively. Paired Student's t tests (n = 15) were performed to assess the significance of the measured intrinsic properties. Trabecular bone microarchitecture is compromised in postmenopausal women, and although this loss is associated with a trend toward reduction in some intrinsic properties (storage modulus), we found no statistically significant changes in bone intrinsic properties between healthy pre- and postmenopausal biopsies in the quasi-static results and frequency-averaged dynamic results.

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confidence: 99%

Intrinsic Material Properties of Trabecular Bone by Nanoindentation Testing of Biopsies Taken from Healthy Women Before and After Menopause

et al. 2012

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“…Several mechanical properties of normal TMJ discs from various species have been evaluated Allen and Athanasiou, 2006;Koolstra and Tanaka, 2009;Kuo et al, 2011;Juran et al, 2013). Anisotropic and heterogeneous properties among diverse region of discs have been highlighted (Kuo et al, 2010;Yuya et al, 2010). Although the physiological functions and mechanical properties of TMJ discs have been documented to some extent, there is a lack of understanding regarding the mechanical properties of pathogenic discs.…”

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confidence: 99%

Deterioration of Mechanical Properties of Discs in Chronically Inflamed TMJ

Wang¹,

Cui²,

Liu³

et al. 2014

J Dent Res

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Temporomandibular joint (TMJ) discs frequently undergo degenerative changes in arthritis. However, the biomechanical properties of pathogenic discs remain to be explored. In this study, we evaluated the effects of chronic inflammation on the biomechanical properties of TMJ discs in rats. Chronic inflammation of TMJs was induced by double intra-articular injections of complete Freund's adjuvant for 5 weeks, and biomechanical properties and ultrastructure of the discs were examined by mechanical testing, scanning electron microscopy, and transmission electron microscopy. The instantaneous compressive moduli of the anterior and posterior bands of discs in inflamed TMJs were decreased significantly compared with those in the control group. The instantaneous tensile moduli of the discs of inflamed TMJs also showed significant decreases in both the anteriorposterior and mesial-lateral directions. The relaxation moduli of the discs of inflamed TMJs showed nearly the same tendency as the instantaneous moduli. The surfaces of the discs of inflamed TMJs became rough and porous due to the loss of the superficial gel-like stratum, with many collagen fibers exposed and degradation of the sub-superficial collagen fibrils. Our results suggested that chronic inflammation of TMJ could lead to deterioration of mechanical properties and alteration of disc ultrastructure, which might contribute to TMJ disc displacement.

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“…Stress relaxation function for a linear viscoelastic material based on the generalized Maxwell model can be expressed as [31]:…”

Section: Stress Relaxation Measurementsmentioning

confidence: 99%

Elevated temperature nanoindentation characterization of poly(para-phenylene vinylene) conjugated polymer films

et al. 2015

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a b s t r a c tTemperature dependent mechanical properties of poly(p-phenylene vinylene) (PPV) were investigated using quasi-static (QS) and dynamic nanoindentation (NI) at temperatures over the range of 25 to 100 C. The reduced modulus decreased from about 4.40 GPa to 3.64 GPa over this temperature range. The plasticity indices at all measurement temperatures were lower than the critical value of 0.875, characterizing material "sink-in", rather than "pile-up" during measurements. The plasticity index showed a non-monotonic trend, with a minimum value at around 70 C. Analysis of indentation stress relaxation data, obtained at different temperatures, was also performed using generalized Maxwell viscoelastic models. From these analyses, a relaxation mode, with a characteristic relaxation time of approximately 0.5 s, was evident. The characteristic time remained relatively unchanged over the temperature range of 25 to 100 C. However, the relaxation modulus associated with this mode showed the expected decrease with increase in temperature.

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Evaluating Anisotropic Properties in the Porcine Temporomandibular Joint Disc Using Nanoindentation

Cited by 19 publications

References 50 publications

Intrinsic Material Properties of Trabecular Bone by Nanoindentation Testing of Biopsies Taken from Healthy Women Before and After Menopause

Intrinsic Material Properties of Trabecular Bone by Nanoindentation Testing of Biopsies Taken from Healthy Women Before and After Menopause

Deterioration of Mechanical Properties of Discs in Chronically Inflamed TMJ

Elevated temperature nanoindentation characterization of poly(para-phenylene vinylene) conjugated polymer films

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