Evaluating nail thickness and stiffness with shear‐wave elastography in nail psoriasis: A preliminary study

İslamoğlu, Zeynep Gizem Kaya; Uysal, Emine; Demirbaş, Abdullah; İslamoğlu, Necat

doi:10.1111/srt.12762

Cited by 4 publications

(3 citation statements)

References 25 publications

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“…To the best of our knowledge, this is the first study that uses SWE in patients with PsO, except for a previous study that used SWE in subjects with nail PsO. 39 In our study, we observed that psoriatic plaque had a marked degree of hardness compared to the skin not affected by dermatopathy before topical treatment with calcipotriol+betamethasone foam. On the contrary, after pharmacological treatment, in a parallel way to a significant reduction of the PASI, there was a statistical significative decrease of plaque skin hardness that highlights a correlation between these parameters, in particular between plaque activity and its hardness.…”

Section: Discussionmentioning

confidence: 44%

Shear wave elastography and microvascular ultrasound in response evaluation to calcipotriol+betamethasone foam in plaque psoriasis

Guazzaroni

Ferrari

Lamacchia

et al. 2020

Postgraduate Medical Journal

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Psoriasis (PsO) is a chronic skin disease. This study aims to evaluate clinical and subclinical response to calcipotriol+betamethasone foam, in patients with PsO, comparing, for the first time, data from microvascular ultrasound (MicroV) and shear wave elastography (SWE) with Psoriasis Area and Severity Index (PASI).MethodsBetween November 2018 and April 2019 in Tor Vergata Hospital (Roma, Italy), we enrolled 26 patients with PsO who were ageds 20–75 years, with PASI score ≥4, candidated for calcipotriol+betamethasone foam treatment. They underwent MicroV and SWE evaluation at baseline (T0) and after 4 weeks of treatment (T4). Clinical follow-up was carried on at T4, T8 and T12. Student’s t-test (p values<0.05 statistically significant) was used to compare SWE and PASI values.ResultsAt T0, SWE stiffness values of target plaques (61.5% on elbows, 23% knees, 7.7% sacrum,7.7% legs) were significantly higher than values under healthy skin. At T4, all patients showed a significant reduction of PASI; MicroV showed reduction in vascularisation of responsive plaques in 85% of cases, only in 15%, the vascularisation degree remained stable; and SWE values of target plaques were significantly lower compared with T0. Only in 7.7%, there was a relapse at T12.ConclusionsCalcipotriol+betamethasone foam is a very effective topical treatment in a short-medium term follow-up in patients with PsO. MicroV and SWE evaluate response to treatment (in term of plaque vascularisation and stiffness), so they could represent promising early indicators of therapeutic response and help the physician to establish a better clinical-therapeutic management of patients with PsO.

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Section: Discussionmentioning

confidence: 44%

Shear wave elastography and microvascular ultrasound in response evaluation to calcipotriol+betamethasone foam in plaque psoriasis

Guazzaroni

Ferrari

Lamacchia

et al. 2020

Postgraduate Medical Journal

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“…A total of 753 articles were screened and 67 articles included, as depicted in the PRISMA flow diagram in Figure 1 9‐75 . The number of articles per technique varied substantially, ranging from 36 for US to just one on PET/CT.…”

Section: Resultsmentioning

confidence: 99%

Imaging of the nail unit in psoriatic patients:A systematic scoping review of techniques and terminology

Ortner

Mandel

Bertugno

et al. 2022

Experimental Dermatology

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Background The growing interest in the visualization of psoriatic nail unit changes has led to the discovery of an abundance of image characteristics across various modalities. Objective To identify techniques for non‐invasive imaging of nail unit structures in psoriatic patients and review extracted image features to unify the diverse terminology. Methods For this systematic scoping review, we included studies available on PubMed and Embase, independently extracted image characteristics, and semantically grouped the identified features to suggest a preferred terminology for each technique. Results After screening 753 studies, 67 articles on the visualization of clinical and subclinical psoriatic changes in the nail plate, matrix, bed, folds and hyponychium were included. We identified 4 optical and 3 radiological imaging techniques for the assessment of surface (dermoscopy [n = 16], capillaroscopy [n = 12]), sub‐surface (ultrasound imaging [n = 36], optical coherence tomography [n = 4], fluorescence optical imaging [n = 3]), and deep‐seated psoriatic changes (magnetic resonance imaging [n = 2], positron emission tomography‐computed tomography [n = 1]). By condensing 244 image feature descriptions into a glossary of 82 terms, overall redundancy was cut by 66.4% (37.5%–77.1%). More than 75% of these image features provide additional disease‐relevant information that is not captured using conventional clinical assessment scales. Conclusions This review has identified, unified, and contextualized image features and related terminology for non‐invasive imaging of the nail unit in patients with psoriatic conditions. The suggested glossary could facilitate the integrative use of non‐invasive imaging techniques for the detailed examination of psoriatic nail unit structures in research and clinical practice.

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“…In dermatology, this parameter is used to evaluate the therapeutic efficacy of various treatments in conditions such as psoriasis, 9,55,66 localized scleroderma, 67 systemic sclerosis, 4,42 hidradenitis suppurativa 10 and atopic dermatitis 64 . In addition, measurements of the skin lesion area, diameter and dimensions are also used in the diagnosis, characterization and evaluation of skin disease treatments 61,65,68–72 …”

Section: Main Metric Parameters Of Analysis By Hfusmentioning

confidence: 99%

High‐frequency ultrasound as a scientific tool for skin imaging analysis

Vergilio

Silva

Jales

et al. 2021

Experimental Dermatology

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Ultrasonic imaging is one of the most important diagnostic tools in clinical medicine due to its cost, availability and good correlation with pathological results. High‐frequency ultrasound (HFUS) is a technique used in skin science that has been little explored, especially in comparison with other sites and imaging techniques. HFUS shows real‐time images of the skin layers, appendages and skin lesions in vivo and can significantly contribute to advances in skin science. This review summarizes the potential applications of HFUS in dermatology and cosmetology, with a focus on quantitative tools that can be used to assess various skin conditions. Our findings showed that HFUS imaging is a reproducible and powerful tool for the diagnosis, clinical management and therapy monitoring of skin conditions. It is also a helpful tool for assessing the performance of dermatological products. This technique may eventually become essential for evaluating the performance of dermatological and cosmetic products.

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Evaluating nail thickness and stiffness with shear‐wave elastography in nail psoriasis: A preliminary study

Cited by 4 publications

References 25 publications

Shear wave elastography and microvascular ultrasound in response evaluation to calcipotriol+betamethasone foam in plaque psoriasis

Shear wave elastography and microvascular ultrasound in response evaluation to calcipotriol+betamethasone foam in plaque psoriasis

Imaging of the nail unit in psoriatic patients:A systematic scoping review of techniques and terminology

High‐frequency ultrasound as a scientific tool for skin imaging analysis

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