Evaluating prognosis after TAVR: The value of left ventricular geometry

Mendoza, Cesar E.; Rivera, Hector

doi:10.1111/jocs.16383

Cited by 1 publication

(2 citation statements)

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“…This transformation has important implications for the clinical outcome of patients after TAVR. 26 (congestive heart failure). 27 This is strong evidence of LVRR after TAVR.…”

Section: Discussionmentioning

confidence: 99%

“…More significantly, the LV geometry patterns of patients in the MAVD group exhibited a significant transformation after TAVR, with more patients developed concentric remodeling and concentric hypertrophy, while eccentric hypertrophy was significantly reduced. This transformation has important implications for the clinical outcome of patients after TAVR 26 . Based on the studies of Palmiere et al, eccentric hypertrophy has higher wall stress, less metabolic and stress reserve, and greater vulnerability to uncompensated LV hypertrophy (congestive heart failure) 27 .…”

Section: Discussionmentioning

confidence: 99%

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Left ventricular reverse remodeling after transcatheter aortic valve replacement for predominant aortic stenosis and mixed aortic valve disease

Huang,

Lai,

et al. 2023

J of Clinical Ultrasound

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BackgroundMixed aortic valve disease (MAVD) is a frequent concomitant valve disease with unique cardiac pathological changes compared to predominant aortic stenosis (PAS). The previous studies about the MAVD are contradictory. Therefore, a new perspective is needed to assess the value of TAVR for this cohort of patients.MethodsFrom January 2018 to December 2021, 90 MAVD patients and 72 PAS patients who underwent TAVR in our hospital were collected. 1:1 propensity score matching analysis was used to control the bias in patient selection. The dynamic changes in left ventricular morphology and hemodynamics were compared by generalized estimating equations. Univariate or multivariate logistic regression analysis was used to screen for independent risk factors for the non‐occurrence of left ventricular reverse remodeling (non‐LVRR).ResultsAfter the matching procedure, 112 patients were included in the analysis (56 in each group). Baseline characteristics were similar between the two groups. LVRR occurred in both groups, but MAVD had greater left ventricular end‐diastolic volume index and left ventricular mass index, a higher incidence of mitral regurgitation (MR), and a more pronounced transformation of ventricular geometry patterns. Post‐operative MR (odd ratio [OR]: 10.05; 95% confidence interval [CI]: 2.08–48.57; p < .001) and coronary artery disease (OR: 2.82; 95% CI: 1.08–7.34; p = .034) were independent risk factors for non‐LVRR.ConclusionLVRR also occurs in patients with MAVD, post‐operative MR and coronary artery disease were independent risk factors for non‐LVRR.

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“…This transformation has important implications for the clinical outcome of patients after TAVR. 26 (congestive heart failure). 27 This is strong evidence of LVRR after TAVR.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%