Evaluating signatures of selection through variation in linkage disequilibrium among different cattle breeds

Kukučková, Veronika; Moravčíková, Nina; Kasarda, Radovan

doi:10.15414/afz.2016.19.si.105-110

Cited by 1 publication

(1 citation statement)

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“…The differences in LD blocks between breeds than indicate differences in selection. This method was used to detect selection signatures in cattle [ 11 , 12 , 13 ], pigs [ 14 ] and horses [ 15 ]. Compared to other popular selection signature estimation methods, the studies using the variance in LD are sparse.…”

Section: Introductionmentioning

confidence: 99%

Within- and between-Breed Selection Signatures in the Original and Improved Valachian Sheep

Mészárosová

Mészáros

Moravčíková

et al. 2022

Animals

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This study explored the genomic diversity and selection signatures in two Slovakian national breeds, the Original Valachian and the Improved Valachian sheep. As they are an important animal genetic resource within the country, but with decreasing population size, our aim is to identify potentially valuable genomic regions. A total of 97 sheep (18 male and 79 female) from the Original Valachian, and 69 sheep (25 male and 44 female) from the Improved Valachian populations were genotyped using the GeneSeek GGP Ovine 50 K chip. The inbreeding levels were assessed with runs of homozygosity (ROH). The selection signatures within breeds were identified based on the top 1% of most homozygous regions within the breed, the so-called ROH islands. The selection signatures between breeds were assessed based on variance in linkage disequilibrium. Overall, we have identified selection signatures with quantitative trait loci (QTL) and genes pointing towards all three production purposes of the Valachian sheep, milk, meat, and wool, including their quality characteristics. Another group with apparent large importance was the various traits related to health and resistance to parasites, which is well in line with the sturdy nature of this breed.

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