Evaluating the possible anticoagulant and antioxidant effects of sulfated polysaccharides from the tropical green alga Caulerpa cupressoides var. flabellata

Costa, Mariana Santana Santos Pereira; Costa, Leandro Silva; Cordeiro, Sara Lima; Almeida-Lima, Jailma; Dantas-Santos, Nednaldo; Magalhães, Kaline Dantas; Sabry, Diego Araújo; Albuquerque, Ivan Rui Lopes; Pereira, M.R.; Leite, Edda Lisboa; Rocha, Hugo Alexandre Oliveira

doi:10.1007/s10811-011-9745-5

Cited by 42 publications

(62 citation statements)

References 39 publications

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“…flabellate are a promising antioxidant agent for preventing the formation of reactive oxygen radicals. These galactans exhibit total antioxidant capacity and ferrous chelating activity but show no superoxide and hydroxyl radical scavenging activity in tests [50]. …”

Section: Biological Activities Of Sulfated Polysaccharides Of Greementioning

confidence: 99%

“…In an APTT test, all of the fractions displayed considerable dose-dependent activities. CCB-F0.3 and CCB-F0.5 showed significant APTT activities similar to that of commercial heparin as well as strong PT activities [50]. Gurgel Rodrigues conclud that C .…”

Section: Biological Activities Of Sulfated Polysaccharides Of Greementioning

confidence: 99%

“…Thus, limited information is available on the relationship between structure and anticoagulant activity of SPs from marine green seaweeds. Two types of SPs with high anticoagulant activities have been identified: sulfated rhamnans from Enteromorpha , Ulva , and Monostroma [74,80,81] and sulfated heterogeneous arabinogalactans from Codium and Caulerpa [50,66,69]. Sulfated rhamnans from Monostroma show more powerful anti-thrombin activities than heparin mediated by heparin cofactor II but weak inhibition of factor Xa through antithrombin.…”

Section: Biological Activities Of Sulfated Polysaccharides Of Greementioning

confidence: 99%

“…The anticoagulant activity of sulfated galactans depends on the nature of the sugar residue, the sulfation position, and the sulfation content [63,70,76]. O -Sulfated 3-linked-galactans show enhanced inhibition of thrombin and factor Xa by antithrombin and/or heparin cofactor II in the intrinsic pathway of blood coagulation [50,77]. High-Mw SPs from Codium with high sulfate content also show higher anticoagulant activities than low-Mw and low sulfate-content SPs [77].…”

Section: Biological Activities Of Sulfated Polysaccharides Of Greementioning

confidence: 99%

“…Table 5 shows descriptions of the chemical compositions and average Mw of four SPs from C. cupressoides . Other detailed structural information on these SPs, such as their sugar linkages, sequence, side and terminal sugars, sulfation position, configuration, and conformation, have not been comprehensively investigated [50]. …”

Section: Structural Diversity Of Green Algal Spsmentioning

confidence: 99%

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Overview on Biological Activities and Molecular Characteristics of Sulfated Polysaccharides from Marine Green Algae in Recent Years

et al. 2014

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Among the three main divisions of marine macroalgae (Chlorophyta, Phaeophyta and Rhodophyta), marine green algae are valuable sources of structurally diverse bioactive compounds and remain largely unexploited in nutraceutical and pharmaceutical areas. Recently, a great deal of interest has been developed to isolate novel sulfated polysaccharides (SPs) from marine green algae because of their numerous health beneficial effects. Green seaweeds are known to synthesize large quantities of SPs and are well established sources of these particularly interesting molecules such as ulvans from Ulva and Enteromorpha, sulfated rhamnans from Monostroma, sulfated arabinogalactans from Codium, sulfated galacotans from Caulerpa, and some special sulfated mannans from different species. These SPs exhibit many beneficial biological activities such as anticoagulant, antiviral, antioxidative, antitumor, immunomodulating, antihyperlipidemic and antihepatotoxic activities. Therefore, marine algae derived SPs have great potential for further development as healthy food and medical products. The present review focuses on SPs derived from marine green algae and presents an overview of the recent progress of determinations of their structural types and biological activities, especially their potential health benefits.

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Section: Biological Activities Of Sulfated Polysaccharides Of Greementioning

confidence: 99%

Section: Biological Activities Of Sulfated Polysaccharides Of Greementioning

confidence: 99%

Section: Biological Activities Of Sulfated Polysaccharides Of Greementioning

confidence: 99%

Section: Biological Activities Of Sulfated Polysaccharides Of Greementioning

confidence: 99%

Section: Structural Diversity Of Green Algal Spsmentioning

confidence: 99%

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Overview on Biological Activities and Molecular Characteristics of Sulfated Polysaccharides from Marine Green Algae in Recent Years

et al. 2014

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Colloid Producing Seaweeds

Pereira

2020

Encyclopedia of Marine Biotechnology

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Biomineralization of gold by Mucor plumbeus: The progress in understanding the mechanism of nanoparticles’ formation

Maliszewska

Tylus

Chęcmanowski

et al. 2017

Biotechnology Progress

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This contribution describes the deposition of gold nanoparticles by microbial reduction of Au(III) ions using the mycelium of Mucor plumbeus. Biosorption as the major mechanism of Au(III) ions binding by the fungal cells and the reduction of them to the form of Au(0) on/in the cell wall, followed by the transportation of the synthesized gold nanoparticles to the cytoplasm, is postulated. The probable mechanism behind the reduction of Au(III) ions is discussed, leading to the conclusion that this process is nonenzymatic one. Chitosan of the fungal cell wall is most likely to be the major molecule involved in biomineralization of gold by the mycelium of M. plumbeus. Separation of gold nanoparticles from the cells has been carried out by the ultrasonic disintegration and the obtained nanostructures were characterized by UV-vis spectroscopy and transmission electron micrograph analysis. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:1381-1392, 2017.

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Evaluating the possible anticoagulant and antioxidant effects of sulfated polysaccharides from the tropical green alga Caulerpa cupressoides var. flabellata

Cited by 42 publications

References 39 publications

Overview on Biological Activities and Molecular Characteristics of Sulfated Polysaccharides from Marine Green Algae in Recent Years

Overview on Biological Activities and Molecular Characteristics of Sulfated Polysaccharides from Marine Green Algae in Recent Years

Colloid Producing Seaweeds

Biomineralization of gold by Mucor plumbeus: The progress in understanding the mechanism of nanoparticles’ formation

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