Evaluating vestibular schwannoma size and volume on magnetic resonance imaging: An inter- and intra-rater agreement study

Vestibular schwannomas: Accuracy of tumor volume estimated by ice cream cone formula using thin-sliced MR images

“…The estimating formulas, such as the ABC/2 formula and ice cream cone method which were calculated by multiple linear measurements of diameters, introduced larger intra- and interobserver variances with 95% limits of intra- and interobserver agreements ranging from ±18.9 to ±28.7%. However, the variances were even comparable to those of the planimetry in previous studies (22.1% to 26%) [ 15 , 31 ].…”

“…In the Bland-Altman analysis, it is not surprised that the inter- and intraobserver variations were higher in smaller size tumor due to the limitation of the minimal unit of measurement (0.01cm for diameter and 0.01mL for volume). The 95% limits of intraobserver agreements of planimetry were ±11.2%, which were within, and even better than, the range of previous studies [ 15 , 31 ]. The estimating formulas, such as the ABC/2 formula and ice cream cone method which were calculated by multiple linear measurements of diameters, introduced larger intra- and interobserver variances with 95% limits of intra- and interobserver agreements ranging from ±18.9 to ±28.7%.…”

Aspirin does not prevent growth of vestibular schwannomas: A case‐control study

“…The subsequent study by Kandathil et al from 2016 aimed to address this potential weakness by using volumetric tumor measurements with a growth definition of >20% increase in tumor volume. Measurement studies have shown that 20% change is a reliable definition of growth when using volumetric measurements . Unfortunately, of the initial 347 participants in the original Kandathil et al study, only 86 had sufficient scans to allow for volume segmentation, meaning the second study may have been underpowered.…”

Diagnostics and therapy of vestibular schwannomas – an interdisciplinary challenge

“…Also in this context, individual factors play a crucial role; none of the described decision-finding schemes is meant to be a dogma. It is more appropriate to consider for example the volume of a tumor as criterion instead of the largest diameter, especially in cases of irregular tumors [ 38 ]. The more complex measurement of the volume is not available in all centers so that we mention here the highest tumor diameter as criterion.…”