Evaluating Vitamin E's Antioxidative Effect on Carbamazepine-Induced Spleen Damage in Rat Models
Asma Basharat Ali,
Nadia Younus,
Sahrish Mukhtar
et al.
Abstract:Background: The spleen is essential for the body’s homeostasis and immune system. Carbamazepine (CBZ) is known to cause toxicity to several organs, including the spleen, through oxidative stress, however, vitamin E (Vit E) is a proven antioxidant against toxins. Thus, this study evaluated the antioxidative effect of Vit E on hematological and splenic toxic changes, caused by carbamazepine in rats.
Methods: This in-vivo preclinical experimental study was conducted from March-June 2020, at Jinnah Medical and Den… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.