Evaluation and quantitative microbial risk assessment of a unique antimicrobial agent for hospital surface treatment

Pérez, Vanessa; Mena, Kristina D.; Watson, Heather; Prater, R. Burt; McIntyre, John L.

doi:10.1016/j.ajic.2015.06.013

Cited by 9 publications

(5 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This process can be done using Markov chain Monte Carlo (MCMC) methods in software such as WinBUGS. The negative binomial model is commonly used in infectious diseases research [ 27 , 28 , 29 , 30 , 31 , 32 , 33 ]; the function is shown in Equation (1):

…”

Section: Methodsmentioning

confidence: 99%

Spatial-Temporal Epidemiology of Tuberculosis in Mainland China: An Analysis Based on Bayesian Theory

Cao

Yang

Wang

et al. 2016

IJERPH

View full text Add to dashboard Cite

Objective: To explore the spatial-temporal interaction effect within a Bayesian framework and to probe the ecological influential factors for tuberculosis. Methods: Six different statistical models containing parameters of time, space, spatial-temporal interaction and their combination were constructed based on a Bayesian framework. The optimum model was selected according to the deviance information criterion (DIC) value. Coefficients of climate variables were then estimated using the best fitting model. Results: The model containing spatial-temporal interaction parameter was the best fitting one, with the smallest DIC value (−4,508,660). Ecological analysis results showed the relative risks (RRs) of average temperature, rainfall, wind speed, humidity, and air pressure were 1.00324 (95% CI, 1.00150–1.00550), 1.01010 (95% CI, 1.01007–1.01013), 0.83518 (95% CI, 0.93732–0.96138), 0.97496 (95% CI, 0.97181–1.01386), and 1.01007 (95% CI, 1.01003–1.01011), respectively. Conclusions: The spatial-temporal interaction was statistically meaningful and the prevalence of tuberculosis was influenced by the time and space interaction effect. Average temperature, rainfall, wind speed, and air pressure influenced tuberculosis. Average humidity had no influence on tuberculosis.

show abstract

…”

Section: Methodsmentioning

confidence: 99%

Spatial-Temporal Epidemiology of Tuberculosis in Mainland China: An Analysis Based on Bayesian Theory

Cao

Yang

Wang

et al. 2016

IJERPH

View full text Add to dashboard Cite

show abstract

“…Along with testing a variety of materials simultaneously, CDC bioreactors grow biofilms in a high shear environment to allow for robust biofilm growth. The coating selected here previously showed high antimicrobial efficacy in hospital settings ( Perez et al, 2015 ; Fitton et al, 2017 ) and exhibited grade 1 toxicity; indicating the coating is below the grade 2 cytotoxic agent threshold, and thus is safe for human contact ( Baxa et al, 2011 ). Since this is a proprietary commercial product, the composition is unfortunately unavailable.…”

Section: Discussionmentioning

confidence: 89%

Antimicrobial Coating Efficacy for Prevention of Pseudomonas aeruginosa Biofilm Growth on ISS Water System Materials

et al. 2022

View full text Add to dashboard Cite

Biofilms can lead to biofouling, microbially induced corrosion, physical impediment and eventual loss in function of water systems, and other engineered systems. The remoteness and closed environment of the International Space Station (ISS) make it vulnerable to unchecked biofilm growth; thus, biofilm mitigation strategies are crucial for current ISS operation and future long duration and deep-space crewed missions. In this study, a space flown bacterial strain of Pseudomonas aeruginosa (PA14) was used as a model organism for its ability to form biofilms. Additionally, a novel antimicrobial coating’s ability to reduce biofilm accumulation on stainless steel, Teflon, titanium, and Inconel (all used in the ISS water treatment and handling systems) was analyzed. Coated materials demonstrated reductions of P. aeruginosa biofilm across all materials when tested in a continuous flow system with tryptic soy broth medium. However, the coating lost efficacy in potato dextrose broth medium. These findings were corroborated via scanning electron microscopy. This study illustrates the fundamental importance of using multiple approaches to test antibiofilm strategies, as well as the specificity in which conditions such strategies can be implemented.

show abstract

“…The technology is currently registered with the US Environmental Protection Agency (85556–1 and 85556–2). Previous work has demonstrated that Goldshield products have bactericidal properties [ [23] , [24] , [25] ]. For example, Goldshield 5 used as a coating on masks had been shown to be an effective antibacterial agent against both gram-positive and gram-negative bacteria [ 26 ].…”

Section: Methodsmentioning

confidence: 99%

Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters

Paranthaman

Peroutka‐Bigus

Larsen

et al. 2022

Materials Today Advances

View full text Add to dashboard Cite

Evaluation and quantitative microbial risk assessment of a unique antimicrobial agent for hospital surface treatment

Cited by 9 publications

References 19 publications

Spatial-Temporal Epidemiology of Tuberculosis in Mainland China: An Analysis Based on Bayesian Theory

Spatial-Temporal Epidemiology of Tuberculosis in Mainland China: An Analysis Based on Bayesian Theory

Antimicrobial Coating Efficacy for Prevention of Pseudomonas aeruginosa Biofilm Growth on ISS Water System Materials

Effective antiviral coatings for deactivating SARS-CoV-2 virus on N95 respirator masks or filters

Contact Info

Product

Resources

About