Évaluation d'un programme de lutte contre les infections nosocomiales à rotavirus dans un service de pédiatrie

Rouget, Florence; Chomienne, F.; Laurens, E.; Radet, C; Seguin, G.

doi:10.1016/s0929-693x(00)90008-3

Cited by 9 publications

(1 citation statement)

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“…In the original reports, nosocomial RVGE was generally defined as disease occurring between 48 to 72 h after admission of the child to hospital, depending on the study [15,26,37]. The prevalence of nosocomial rotavirus infections among hospitalized children admitted for a diagnosis other than diarrhea ranged from 2.9% to 6.6% in four studies from France [26,27,37,38]. Three studies from five countries (Austria, France, Germany, Spain and Switzerland) examined the proportion of nosocomial RVGE among cases of acute nosocomial gastroenteritis [15,26,30].…”

Section: Resultsmentioning

confidence: 99%

Burden of community-acquired and nosocomial rotavirus gastroenteritis in the pediatric population of Western Europe: a scoping review

Ogilvie¹,

Khoury²,

Goetghebeur³

et al. 2012

BMC Infect Dis

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Background Rotavirus affects 95% of children worldwide by age 5 years and is the leading cause of severe dehydrating diarrhea. The objective of this review was to estimate the burden of rotavirus gastroenteritis (RVGE) in the Western European pediatric population. Methods A comprehensive literature search (1999-2010) was conducted in PubMed and other sources (CDC; WHO, others). Data on the epidemiology and burden of RVGE among children < 5 years-old in Western Europe --including hospital-acquired disease--were extracted. Results 76 studies from 16 countries were identified. The mean percentage of acute gastroenteritis (AGE) cases caused by rotavirus ranged from 25.3%-63.5% in children < 5 years of age, peaking during winter. Incidence rates of RVGE ranged from 1.33-4.96 cases/100 person- years. Hospitalization rates for RVGE ranged from 7% to 81% among infected children, depending on the country. Nosocomial RVGE accounted for 47%-69% of all hospital-acquired AGE and prolonged hospital stays by 4-12 days. Each year, RVGE incurred $0.54- $53.6 million in direct medical costs and $1.7-$22.4 million in indirect costs in the 16 countries studied. Full serotyping data was available for 8 countries. G1P[8], G2P[4], G9P[8], and G3P[8] were the most prevalent serotypes (cumulative frequency: 57.2%- 98.7%). Serotype distribution in nosocomial RVGE was similar. Conclusions This review confirms that RVGE is a common disease associated with significant morbidity and costs across Western Europe. A vaccine protecting against multiple serotypes may decrease the epidemiological and cost burden of RVGE in Western Europe.

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