2023
DOI: 10.1039/d2ra05808a
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Evaluation of a biosensor-based graphene oxide-DNA nanohybrid for lung cancer

Abstract: Lung cancer is nowadays among the most prevalent diseases worldwide and features the highest mortality rate among various cancers, indicating that early diagnosis of the disease is of paramount importance.

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Cited by 57 publications
(5 citation statements)
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References 119 publications
(185 reference statements)
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“…GO offers several advantages over pure graphene, including improved processability, versatility, and cost-effectiveness ( Grewal et al, 2018 ). Specifically, GO possesses interesting properties such as high hydrophilicity, solubility in water, large surface area, excellent dispersibility, and biocompatibility, making it an attractive material for various applications in fields such as energy storage ( Safari and Mazloom, 2023 ), biosensors ( Kadhim et al, 2023 ), water purification ( Tene et al, 2022a ), electronic devices ( Wu et al, 2023 ), and drug delivery ( Sontakke et al, 2023 ).…”
Section: Introductionmentioning
confidence: 99%
“…GO offers several advantages over pure graphene, including improved processability, versatility, and cost-effectiveness ( Grewal et al, 2018 ). Specifically, GO possesses interesting properties such as high hydrophilicity, solubility in water, large surface area, excellent dispersibility, and biocompatibility, making it an attractive material for various applications in fields such as energy storage ( Safari and Mazloom, 2023 ), biosensors ( Kadhim et al, 2023 ), water purification ( Tene et al, 2022a ), electronic devices ( Wu et al, 2023 ), and drug delivery ( Sontakke et al, 2023 ).…”
Section: Introductionmentioning
confidence: 99%
“…Photosensitizers of the third generation typically apply to improvements such as biological conjugates (e.g. antibody conjugate, liposome conjugate) and built-in capabilities for photo quenching or bleaching (Kianfar, 2022;Salahdin et al, 2022;Kianfar et al, 2022b;Isola et al, 2022;Fattah et al, 2023).The target-specific PDT uses photosensitizers that combine the sensitivity of an over-expressed cell marker with the phototoxic properties of the conjugated PDT photosensitizer with the antibody-or antisense-conjugated photosensitizers (Kadhim et al, 2023;Al-Awsi et al, 2023). A quick analysis of the advantages and deficiencies of each is worthwhile (Table 2).…”
Section: Photosynthesize (Ps) For Cancermentioning
confidence: 99%
“…Among the problems that face graphene-based devices is the method of transferring the graphene product, which may sometimes lead to cracks, breakage, or impurities entering the structure of the graphene. Therefore, it became necessary to find an effective method of transfer to avoid these problems, for example, making the graphene grow on the surface of another substrate [119]. Perhaps one of the biggest challenges facing the use of graphene in electronic industries is the high production cost of producing large quantities of graphene, which depends on the type of substrates and energy sources used in preparing graphene [120].…”
Section: Challenges On Graphene Aerogel-based Devicesmentioning
confidence: 99%