Evaluation of Analgesic Activity and Phytochemical Screening of Clitoria ternatea Linn

Chavan, Seema; Jadhav, Ravindra S.; Kharat, Deepak; Mankar, S. D.; Godge, Rahul K.

doi:10.9734/bjpr/2015/13593

Cited by 8 publications

(12 citation statements)

References 9 publications

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“…We established that extracts of M. sativa and M. lupulina were active, though limitedly, against mentioned bacteria except for E. coli. Chavan et al (2015) concluded that alfalfa plant may be a new source for novel antibacterial compound discovery for treating drug-resistant human pathogens as the methanol extracts of alfalfa leaves exhibited potent antibacterial activity. Lobanova and Yakimova (2012) observed that Astragalus glycyphyllos L. showed the antimicrobial activity against S. aureus and K. pneumoniae.…”

Section: Antimicrobial Activitymentioning

confidence: 99%

“…However, not only pulses but also some perennial legumes have been consumed as edible or medicinal plants since ancient times, although the composition of their nutritious substances or existence of bioactive compounds was unknown. Literature data confirm that leaves, young plants (shoots) and flowers of different genera and species of perennial legumes have been used in food or phytotherapy in different countries and ages (Chavan et al 2015;Lim 2014;Small 2011). Nowadays, leaves and seeds of some species (e.g.…”

Section: Introductionmentioning

confidence: 98%

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Perennial legumes as a source of ingredients for healthy food: proximate, mineral and phytoestrogen composition and antibacterial activity

et al. 2017

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Perennial legumes have been used as edible or medicinal plants since ancient times. The focus of the current study are perennial legumes-Trifolium pratense L., T. medium L., Medicago sativa L., M. lupulina L., Onobrychis viciifolia Scop., Astragalus glycyphyllos L. and A. cicer L.-of branching stage as a potential source of value-added ingredients for healthy food. Freeze-dried samples were analysed for proximal composition, mineral, isoflavone and coumestrol contents as well as for antimicrobial activity. Legumes were protein-rich (23.0/100 g on average). Mineral contents in 100 g of plant dry matter averaged: K 2.64 g, Ca 1.81 g, Mg 0.475 g, P 0.324 g, Zn 2.76 mg and Fe 37.8 mg. According to the total amount of phytoestrogens, the species ranked as follows: T. medium (34.4 mg/g)) T. pratense) O. viciifolia C M. sativa = A. cicer = M. lupulina C A. glycyphyllos (0.207 mg/ g). Extracts of legumes, especially that of O. viciifolia, exhibited noticeable potency to inhibit the growth of Grampositive and Gram-negative bacteria. Perennial legumes of branching stage can be used as protein, mineral and phytoestrogen rich source for food ingredients and supplements.

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Section: Antimicrobial Activitymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

Perennial legumes as a source of ingredients for healthy food: proximate, mineral and phytoestrogen composition and antibacterial activity

et al. 2017

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“…The methanol extract of this plant created inhibition zones of 23, 22 and 23 mm in diameter for Escherichia coli, Pseudomonas aeruginosa and Streptococcus aureus, respectively. The authors also reported an MIC of 37 μg/ml for E. coli, 12.03 mg/ml for P. aeruginosa and 111 μg/ml for S. aureus (Chavan et al, 2015). The antibacterial effect of this plant could be due to their phenolic compounds.…”

Section: Discussionmentioning

confidence: 88%

Phytochemical evaluation and antibacterial effects of Medicago sativa, Onosma sericeum, Parietaria judaica L., Phlomis persica and Echinophora platyloba DC. on Enterococcus faecalis

Khaledi

Asadi-Samani

et al. 2018

Biomed. Res. Ther.

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Background: Since drug resistance has become one of the predominant problems of health worldwide, it is necessary to use new methods to combat drug-resistant bacteria. In this regard, medicinal plants are considered one of the richest sources to produce antibiotics. The aim of this study was to investigate the antibacterial effects as well as total phenolic and flavonoid contents of a number of medicinal plants collected from the Chaharmahal and Bakhtiari provinces of India, in order to investigate their potential use for the production of new antibiotics. Materials and Methods: In this experimental study, the maceration method was used to prepare hydroalcoholic extract of Medicago sativa, Onosma sericeum, Parietaria judaica L., Phlomis persica and Echinophora platyloba DC. The effect of these plants on Enterococcus faecalis (ATCC 29212) was investigated. To determine the antibacterial effect of the extracts, broth microdilution in sterile 96-well plate was used according to the McFarland standard (105 CFU/ml). The total phenolic content was assayed by using the Folin-Ciocalteu colorimetric method and expressed in terms of gallic acid equivalent. The total flavonoid content was assayed by aluminum chloride colorimetric method and expressed in terms of rutin equivalent. Results: Based on the results of this study, the 512, 256, 128, 32 and 32 µg/ml doses were determined to be the minimum inhibitory concentrations (MICs), and the 1024, 1024, 512, 128 and 128 μg/ml doses were derived as the minimum bactericidal concentration (MBCs) of M. sativa, O. Sericeum, P. judaica, P. persica and E. platyloba, respectively. E. faecalis and P. judaica contained the highest total phenolic content and flavonoid content, respectively. Conclusion: Given the comparatively higher antibacterial effect of P. persica and E. platyloba, as well as the presence of phenolic and flavonoid compounds in these plants, it is recommended that these plants be further investigated in feasibility studies for the production of new antibiotics.

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“…In this study, the antibacterial effects of Medicago sativa extract on E.coli and Pseudomonas aeruginosa were studied by MIC and disk diffusion methods. The results showed inhibitory and antibacterial effect of Medicago sativa extract on the bacterial growth (23). In a study by George p et al, performed in India in 2014, the antibacterial effect of Medicago sativa extract on different bacteria such as Bacillus licheniformis, Pseudomonas aeruginosa, Lactococcus lactis, Klebsiella pneumonia, Bacillus cereus was investigated.…”

Section: Resultsmentioning

confidence: 99%

Antibacterial effect of Medicago sativa extract on the common bacterial in sinusitis infection

Chegini

Oshaghi

Boshagh

et al. 2018

IJBMPH

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Introduction: Sinusitis is a serious health hazard that is caused by inflammation of the surrounding sinus. Bacterial infection due to Streptococcus pneumonia microorganisms, Haemophilus influenza, Moraxella catarrhalis and Staphylococcus aureus is one of the factors causing sinusitis and bronchitis. Medicago sativa is known as a precious medicinal plant. The purpose of this study is to investigate the antibacterial effect of Medicago sativa extract on common bacteria in sinusitis and bronchitis. Methods: In this experimental study, after root extraction of the plant by maceration method, first the quantitative Minimum Inhibitory growth Concentration (MIC) test was carried out and then disc diffusion quality test was performed with the observance of standard strains for Streptococcus pneumonia, Haemophilus influenza, Moraxella catarrhalis, and Staphylococcus aureus. Result:The results showed that MIC of Medicago sativa root extract against Streptococcus pneumoniae, Haemophilus influenza and Moraxella catarrhalis was 125 mg/ml. Furthermore, the extract did not affect Staphylococcus aureus, and in all of the tubes turbidity and growth were observed. In the disc diffusion method, the diameter of the inhibition zone was 16 mm for Moraxella catarrhalis, 13 mm for Streptococcus pneumoniae and 10 mm for Haemophilus influenza, and for Staphylococcus aureus, no inhibition zone was found around the disk containing the extract. Conclusion:The results of this study showed the inhibitory effect of Medicago sativa root extract on Streptococcus pneumoniae, Haemophilus influenza and Moraxella catarrhalis. By extracting the important compounds of this plant, we can hope to make a suitable drug for the treatment of sinusitis.

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Evaluation of Analgesic Activity and Phytochemical Screening of Clitoria ternatea Linn

Cited by 8 publications

References 9 publications

Perennial legumes as a source of ingredients for healthy food: proximate, mineral and phytoestrogen composition and antibacterial activity

Perennial legumes as a source of ingredients for healthy food: proximate, mineral and phytoestrogen composition and antibacterial activity

Phytochemical evaluation and antibacterial effects of Medicago sativa, Onosma sericeum, Parietaria judaica L., Phlomis persica and Echinophora platyloba DC. on Enterococcus faecalis

Antibacterial effect of Medicago sativa extract on the common bacterial in sinusitis infection

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