Since the 2011 Tohoku-Oki Earthquake, evaluations based on a tsunami simulation approach have had a very important role in promoting tsunami disaster prevention measures in the case of mega-thrust earthquakes. When considering tsunami disaster prevention measures based on the knowledge obtained from tsunami simulations, it is important to carefully examine the type of tsunami source model. In current tsunami simulations, there are various ways to set the tsunami source model, and a considerable difference in tsunami behavior can be expected among the tsunami source models. In this study, we carry out a tsunami simulation of the 2011 Tohoku-Oki Earthquake around Fukushima Daiichi (I) Nuclear Power Plant and Fukushima Daini (II) Nuclear Power Plant in Fukushima Prefecture, Japan, using several tsunami source models, and evaluate the difference in the tsunami behavior in the tsunami inundation process. The results show that for an incoming tsunami inundating an inland region, there are considerable relative differences in the maximum tsunami height and wave pressure. This suggests that there could be false information used in promoting tsunami disaster prevention measures in the case of mega-thrust earthquakes, depending on the tsunami source model.