Evaluation of different diagnostic methods for the detection of Mycobacterium avium subsp. paratuberculosis in boot swabs and liquid manure samples

Hahn, Nathalie; Failing, Klaus; Eisenberg, Tobias; Schlez, Karen; Zschöck, P.M.; Donat, Karsten; Einax, Esra; Köhler, Heike

doi:10.1186/s12917-017-1173-6

Cited by 18 publications

(23 citation statements)

References 37 publications

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“…Environmental sampling and assessment protocols for MAP detection has been developed [ 53 , 54 ]). Other recent, MAP studies related to environments include environmental detection of MAP in some matrices such as drylot pens, dairy herds’ paddock, milking facilities, anaerobic digestion of slurry from MAP-infected farm, manure storage, lactating cow surroundings, housing (freestall, loose housing, or tiestall), liquid manure and boot swabs [ 18 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 ].…”

Section: Resultsmentioning

confidence: 99%

Systematic Assessment of Mycobacterium avium Subspecies Paratuberculosis Infections from 1911–2019: A Growth Analysis of Association with Human Autoimmune Diseases

Ekundayo

Okoh

2020

Microorganisms

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Mycobacterium avium subsp. paratuberculosis (MAP) is an understudied pathogen worldwide with continuous implications in human autoimmune diseases (ADs). The awareness of MAP appears to be low in many places and its research is at infant stage in many countries. The lack of worldwide coverage of the MAP research landscape calls for urgent research attention and prioritization. This present study aimed to assess MAP global research productivity with an emphasis on its implications in ADs via bibliometric and growth analytic frameworks from authors, countries, institutions, international, disciplines and collaboration network perspectives. MAP primary articles were retrieved from the Scopus database and the Web of Science from 1911 to 2019 via title-specific algorithm. Analytic results of dataset yielded a total of 3889 articles from 581 journals and 20.65 average citations per documents. The annual growth rate of MAP research for the period was 6.31%. Based on a country’s productivity (articles (%), freq. of publication (%)), the USA (887 (22.81%), 26.72%), and Australia (236 (6.07%), 6.07%) ranked the top 2 countries but Egypt and Germany had the highest average growth rate (AGR, 170%) in the last 3 years. MAP studies are generally limited to Europe, Australia, Asia, South America and few nations in Africa. It had positive growth rate (30%–100%) in relation to type 1 diabetes mellitus and rheumatoid arthritis ADs; food science and technology, immunology, agriculture, pathology, and research and experimental medicine, wildlife, environments, virulence, disease resistance, meat and meat products, osteopontin, waste milk and slurry/sludge digestion subjects; but negative growth (−130% to −30%) in ulcerative colitis and Parkinson’s disease and no growth in multiple sclerosis, sarcoidosis, thyroid disorders, psoriasis, and lupus. The mapping revealed a gross lack of collaboration networking in terms of authorship, (intra- and inter-) nationally and institutionally with a generalized collaboration index of 1.82. In conclusion, inadequate resources-, knowledge- and scientific-networking hampered growth and awareness of MAP research globally. The study recommends further research to strengthen evidence of MAP’s epidemiologic prevalence in ADs and proffer practical solution(s) for drug development and point-of-care diagnostics amongst other extended themes.

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Section: Resultsmentioning

confidence: 99%

Systematic Assessment of Mycobacterium avium Subspecies Paratuberculosis Infections from 1911–2019: A Growth Analysis of Association with Human Autoimmune Diseases

Ekundayo

Okoh

2020

Microorganisms

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“…Last, we did not include environmental sampling in the present work, as it will be the subject of a separate piece of work within the same project. The use of environmental testing to identify the presence of MAP has been increasingly investigated in recent years (Lavers et al, 2013;Hahn et al, 2017) and could contribute to more cost-effective testing strategies when combined with traditional serum or milk sampling activities.…”

Section: Discussionmentioning

confidence: 99%

Modeling of alternative testing strategies to demonstrate freedom from Mycobacterium avium ssp. paratuberculosis infection in test-negative dairy herds in the Republic of Ireland

Meyer

McAloon

Tratalos

et al. 2019

Journal of Dairy Science

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“…Field cultures were obtained from the mycobacteria collections of the Hessian State Laboratory, Giessen, Germany. They were collected in the course of voluntary MAP surveillance programmes in three German federal states (Hesse, Thuringia and Saxony; Eisenberg et al 2013;Donat et al 2016;Hahn et al 2017). The respective cultures were primarily cultivated on Herrold's egg yolk medium (HEYM) agar slants supplemented with mycobactin J (MJ; HEYM-MJ; BD, Heidelberg, Germany) using faecal or environmental samples originating from dairy herds (n = 81), where growth was observed within 6-8 weeks.…”

Section: Map Strains/culturesmentioning

confidence: 99%

Development of a hierarchical typing approach for Mycobacterium avium subsp. paratuberculosis (MAP) and characterization of MAP field cultures from Central Germany

Fawzy

Zschöck²,

Ewers

et al. 2020

J. Appl. Microbiol.

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Aims: Development of a novel hierarchical Mycobacterium avium subsp. paratuberculosis (MAP) typing approach and characterization of MAP field cultures in Central Germany. Methods and Results: By combining single nucleotide polymorphisms (SNPs) and mycobacterial interspersed repetitive unit-variable number tandem repeat, we developed a highly discriminating and phylogenetically accurate hierarchical MAP typing approach. Moreover, a novel stepwise workflow was employed to reduce the number of SNP reactions required making the typing approach more affordable. MAP field cultures (n = 142) from dairy herds in Central Germany were classified as cattle type and showed a high level of heterogeneity. Intra-herd multiple genotypes were evident in (13-25%) of the investigated herds. Conclusions: The hierarchical MAP typing approach proved to be useful in fine discrimination between MAP cultures within limited geographical regions. This could potentially be used in unravelling MAP transmission chains in the respective regions. The observed heterogeneity in some herds is assumed to be due to either multiple introductions through inter-herd trade or intra-herd evolution over time. Significance and Impact of the Study: Future MAP epidemiological studies will benefit from the advantages of the novel hierarchical typing approach. The SNP number reduction approach employed here could be extrapolated for other analogous pathogens.

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Evaluation of different diagnostic methods for the detection of Mycobacterium avium subsp. paratuberculosis in boot swabs and liquid manure samples

Cited by 18 publications

References 37 publications

Systematic Assessment of Mycobacterium avium Subspecies Paratuberculosis Infections from 1911–2019: A Growth Analysis of Association with Human Autoimmune Diseases

Systematic Assessment of Mycobacterium avium Subspecies Paratuberculosis Infections from 1911–2019: A Growth Analysis of Association with Human Autoimmune Diseases

Modeling of alternative testing strategies to demonstrate freedom from Mycobacterium avium ssp. paratuberculosis infection in test-negative dairy herds in the Republic of Ireland

Development of a hierarchical typing approach for Mycobacterium avium subsp. paratuberculosis (MAP) and characterization of MAP field cultures from Central Germany

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