Evaluation of Dosimetric Parameters and Disease Response After 125Iodine Transperineal Brachytherapy for Low- and Intermediate-Risk Prostate Cancer

Radiation oncology and medical physicists quality assurance in British Columbia Cancer Agency Provincial Prostate Brachytherapy Program

“…Our implant procedure has been previously described in detail (3,10). In brief, radioactive seeds are implanted using a preplanned, ultrasound (US)-guided transperineal technique described by the Seattle group.…”

Evaluating the Phoenix Definition of Biochemical Failure After 125I Prostate Brachytherapy: Can PSA Kinetics Distinguish PSA Failures From PSA Bounces?

“…As of March 2009, more than 2,500 men have been treated with 125 I monotherapy. In previous reports, our group has provided detailed oncologic outcomes for a cohort consisting of the first of 1,006 consecutive brachytherapy patients (18,19). In those reports, 57 men were identified whose PSA profile triggered the nadir PSA + 2 ng/mL À1 definition.…”

Radiation Therapy for Prostate Cancer

“…Numerous studies have confirmed D 90 (the minimum dose received by 90% of the prostate volume) and V 100 (percentage of the prostate volume receiving 100% of the prescribed dose) are correlated with outcome [54][55][56].…”