A field experiment was carried out during the season 2020/2021 in Anbar Governorate - Heet district - Sweeb region to study the effect of levels of nitrogen, phosphorus and potassium on some yield characteristics of quinoa plants using three levels of nitrogen (50, 100, 150) kg h−1 and symbolized by (N1, N2, N3) respectively and three levels of phosphorus (22, 44 and 66) kg P ha−1 and took the symbolized (P1, P2, P3) and three levels of potassium (33.2, 66.2, 99.2) kg K.ha−1 The experiment was designed according to the randomized complete block design (RCBD) with three replications. The results of the experiment showed that the highest percentage of protein in quinoa grains reached 16.50% at low fertilizer levels of nitrogen and high levels of phosphorus and potassium when treated N1P3K3, As for the oil percentage, the low levels of nitrogen, phosphorus and potassium gave the highest oil percentage of 4.39%, as well as the phenols gave the highest value of 74.73 mg Gallic gm−1 at medium levels of nitrogen and low levels of potassium and phosphorus 34.20 mg Gallic gm−1 when treated N2P1K1. As for the flavonoids, it gave the highest value of 34.20 mg Rutin gm−1 It was found that there was a strong positive correlation between phenols and flavonoids of r = 0.78. As for saponins it increased with a decrease in the level of nitrogen and an increase in the levels of phosphorus and potassium, as it gave the highest value of 8.21%, that is, when treating N2P1K1, and it was found that there was a strong negative correlation between The percentage of saponins and the percentage of nitrogen in seeds had a value of r=-0.75.