Evaluation of ghee based formulation for wound healing activity

Prasad, V. Satya; Dorle, A. K.

doi:10.1016/j.jep.2006.02.006

Cited by 54 publications

(35 citation statements)

References 17 publications

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“…A measured amount of ointment(s) was placed in the fixed glass slides, and the movable slide with the pan was placed over the fixed slide, so that the ointments were sandwiched between the two slides for 5 min. A 50 g weight was placed on the top of two plates and the time required by the top plate to cover a distance of 10 cm was recorded (Prasad and Dorle, 2006). The spreadability was determined by the formula: S ¼M/T, where S is the spreadability in g/s, M is the mass in grams and T is the time in seconds.…”

Section: Stability Of Formulationmentioning

confidence: 99%

Evaluation of the wound healing activity of methanol extract of Pedilanthus tithymaloides (L.) Poit leaf and its isolated active constituents in topical formulation

Ghosh

Samanta

Mandal

et al. 2012

Journal of Ethnopharmacology

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Section: Stability Of Formulationmentioning

confidence: 99%

Evaluation of the wound healing activity of methanol extract of Pedilanthus tithymaloides (L.) Poit leaf and its isolated active constituents in topical formulation

Ghosh

Samanta

Mandal

et al. 2012

Journal of Ethnopharmacology

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“…Serial sections of 10 mm were cut, and stained with hematoxylin and eosin. The sections were studied under light microscope (Prasad & Dorle, 2006). Table 2.…”

Section: Histopathological Examinationsmentioning

confidence: 99%

Wound healing activity of extracts derived fromShorea robustaresin

Khan

Ali

Pundarikakshudu

2015

Pharmaceutical Biology

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Context: Shorea robusta Gaertn.f. (Dipterocarpaceae) resin is used for treating infected wounds and burns by tribals in India. Objectives: The objective of this study was to investigate wound-healing activity of S. robusta resin extracts and essential oil in rats. Materials and methods: Methanol extract (SRME), petroleum ether, benzene insoluble fraction of methanol extract (SRPEBIME), and essential oil (SREO) of S. robusta resin were incorporated in soft yellow paraffin (10% w/w) and applied once daily on incision and excision wounds of Wistar rats. Framycetin ointment (1.0% w/w) was applied to the standard group. Tensile strength (on the 10th day), wound contraction, and scar area (on the 14th day) were recorded. On the 15th day, granulation tissues of excision wounds were analyzed for total protein, hydroxyproline, and hexosamine contents and activities of lipid peroxidation and super oxide dismutase (SOD). Histopathology of the wounds was also studied. Results and discussion: SRPEBIME and SREO healed incision and excision wounds faster than plain ointment base and framycetin. Tensile strength of SRPEBIME-treated incision wounds was 53% higher than that of control animals. In excision wounds, wound contraction and scar areas were found to be 99% and 7.7 mm 2 (SRPEBIME) and 71.7% and 21 mm 2 (control). Protein and hydroxyproline contents were higher in SRPEBIME (20.8 and 3.5% w/w) and SREO (17.4 and 2.8% w/w) groups as against 9.95 and 1.48% w/w in control groups. Histopathology revealed complete epithelization and new blood vessel formation in SRPEBIME groups. Discussion and conclusion: SRPEBIME and SREO have significant wound-healing activities on incision and excision wounds.

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“…Cow ghee's regenerative properties are also useful for healing wounds and promoting the growth of healthy cells. This wound healing ability has also been clinically proven [25,26]. Cow ghee's cold, oily qualities help protect the body's mucous membranes and ensure its usefulness in any condition with burning sensations.…”

Section: Cow Ghee (Goghrita)mentioning

confidence: 99%

Dietary Considerations of Wound Healing in Ayurveda

Wali¹

2013

J Nutr Food Sci

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Sciences Tonni and Wali et al., J Nutr Food Sci 2013, 3:5 http://dx.doi.org/10.4172/2155-9600.1000227 *Corresponding author: Sanjeev S Tonni, Department of Swasthavritta, KLE University's Shri BMK Ayurveda College and Hospital, Shahapur, Belgaum-590003, Karnataka, India, E-mail: sanjeevtonni@yahoo.com AbstractWound healing has been the burning problem in a surgical practice because of a remarkable increase in the number of traumatic cases. A wound causes a number of changes in the body that can affect the healing process, including changes in energy, protein, carbohydrate, fat, vitamin and mineral metabolism.Various ayurvedic literatures, particularly, Sushrut samhita, which is said to be a ancient textbook of surgery in Ayurveda, has mentioned about the diet for the person suffering from the wound, and the author said that diet plays a very important role in the wound healing process. Sushruta-The father of surgery has scientifically classified it in a systemic manner, whose wealth of clinical material and the principles of management are valid even today. Shalya Tantra (surgical branch in ayurvedic science) is one of the important branch of ayurveda, in which surgical and para-surgical techniques has described for management of various diseases. Vrana is the most important and widely described chapter of Shalya Tantra. Vrana (wound) is one of them, which have been managed by human being from starting of civilization. Under the circumstances, the first thing which the men came across was the injury from different sources which caused him the vrana. Vrana is seen as debilitating and scaring disorder, usually seen affecting the human being at any age. Well balanced nutrition plays an essential role in the wound healing.

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Evaluation of ghee based formulation for wound healing activity

Cited by 54 publications

References 17 publications

Evaluation of the wound healing activity of methanol extract of Pedilanthus tithymaloides (L.) Poit leaf and its isolated active constituents in topical formulation

Evaluation of the wound healing activity of methanol extract of Pedilanthus tithymaloides (L.) Poit leaf and its isolated active constituents in topical formulation

Wound healing activity of extracts derived fromShorea robustaresin

Dietary Considerations of Wound Healing in Ayurveda

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