Evaluation of larvicidal enhanced activity of sandalwood oil via nano-emulsion against Culex pipiens and Ades aegypti

Bosly, Hanan Abo El-Kassem

doi:10.1016/j.sjbs.2022.103455

Cited by 7 publications

(3 citation statements)

References 55 publications

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“…Taking this into account, the new HT-NE development in the present study showed suitable parameters with mean values of PDI of 0.267 ± 0.008 for 21 days. In a previous study by Bosly [35], in 2022, an NE using a high sonication method to obtain nanoparticles was prepared, similar to our study. The authors confirmed the homogeneity, stability, and adequate particle distribution of the NE with a PDI of 0.342, which was optimized, acquiring a PDI of 0.263 [35].…”

Section: Discussionsupporting

confidence: 58%

“…In a previous study by Bosly [35], in 2022, an NE using a high sonication method to obtain nanoparticles was prepared, similar to our study. The authors confirmed the homogeneity, stability, and adequate particle distribution of the NE with a PDI of 0.342, which was optimized, acquiring a PDI of 0.263 [35]. The outcome of our 90-day characterization period reveals a PDI of 0.584.…”

Section: Discussionsupporting

confidence: 58%

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Formulation of a Novel Hesperetin-Loaded Nanoemulsion and Its Promising Effect on Osteogenesis

Mancim-Imbriani,

Duarte,

Di Filippo

et al. 2024

Pharmaceutics

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Alternative therapies associating natural products and nanobiotechnology show new perspectives on controlled drug release. In this context, nanoemulsions (NEs) present promising results for their structural design and properties. Hesperetin (HT), a flavonoid mainly found in citrus fruits, presents highlighted bone benefits. In this context, we developed a hesperetin-loaded nanoemulsion (HT-NE) by sonication method and characterized it by dynamic light scattering, analyzing its encapsulation efficiency, and cumulative release. The biocompatibility in human osteoblasts Saos-2-like was evaluated by the cytotoxicity assay and IC50. Then, the effects of the HT-NE on osteogenesis were evaluated by the cellular proliferation, calcium nodule formation, bone regulators gene expression, collagen quantification, and alkaline phosphatase activity. The results showed that the formulation presented ideal values of droplet size, polydispersity index, and zeta potential, and the encapsulation efficiency was 74.07 ± 5.33%, showing a gradual and controlled release. Finally, HT-NE was shown to be biocompatible and increased cellular proliferation, and calcium nodule formation, regulated the expression of Runx2, ALPL, and TGF-β genes, and increased the collagen formation and alkaline phosphatase activity. Therefore, the formulation of this NE encapsulated the HT appropriately, allowing the increasing of its effects on mechanisms to improve or accelerate the osteogenesis process.

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Section: Discussionsupporting

confidence: 58%

Section: Discussionsupporting

confidence: 58%

Formulation of a Novel Hesperetin-Loaded Nanoemulsion and Its Promising Effect on Osteogenesis

Mancim-Imbriani,

Duarte,

Di Filippo

et al. 2024

Pharmaceutics

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“…Moreover, nanoformulated natural products have proven effective against other disease-carrying mosquitoes, such as Aedes sp. [ 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 ], and Culex sp. [ 78 , 79 , 80 ].…”

Section: Plants and Nano Formulationsmentioning

confidence: 99%

Tiny Green Army: Fighting Malaria with Plants and Nanotechnology

Moraes-de-Souza,

de Moraes,

Silva

et al. 2024

Pharmaceutics

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Malaria poses a global threat to human health, with millions of cases and thousands of deaths each year, mainly affecting developing countries in tropical and subtropical regions. Malaria’s causative agent is Plasmodium species, generally transmitted in the hematophagous act of female Anopheles sp. mosquitoes. The main approaches to fighting malaria are eliminating the parasite through drug treatments and preventing transmission with vector control. However, vector and parasite resistance to current strategies set a challenge. In response to the loss of drug efficacy and the environmental impact of pesticides, the focus shifted to the search for biocompatible products that could be antimalarial. Plant derivatives have a millennial application in traditional medicine, including the treatment of malaria, and show toxic effects towards the parasite and the mosquito, aside from being accessible and affordable. Its disadvantage lies in the type of administration because green chemical compounds rapidly degrade. The nanoformulation of these compounds can improve bioavailability, solubility, and efficacy. Thus, the nanotechnology-based development of plant products represents a relevant tool in the fight against malaria. We aim to review the effects of nanoparticles synthesized with plant extracts on Anopheles and Plasmodium while outlining the nanotechnology green synthesis and current malaria prevention strategies.

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Effects of extended dietary supplementation with Santalum album essential oil on hemato-biochemical changes, innate immune response, antioxidant status, and expression of related gene in Nile tilapia (Oreochromis niloticus)

Mansour,

Arisha,

Abdelaziz

et al. 2024

Fish Physiol Biochem

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Evaluation of larvicidal enhanced activity of sandalwood oil via nano-emulsion against Culex pipiens and Ades aegypti

Cited by 7 publications

References 55 publications

Formulation of a Novel Hesperetin-Loaded Nanoemulsion and Its Promising Effect on Osteogenesis

Formulation of a Novel Hesperetin-Loaded Nanoemulsion and Its Promising Effect on Osteogenesis

Tiny Green Army: Fighting Malaria with Plants and Nanotechnology

Effects of extended dietary supplementation with Santalum album essential oil on hemato-biochemical changes, innate immune response, antioxidant status, and expression of related gene in Nile tilapia (Oreochromis niloticus)

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