Evaluation of local trace element status and 8-Iso-prostaglandin F2α concentrations in patients with Tinea pedis

Miraloğlu, Meral; Kurutaş, Ergül Belge; Öztürk, Perihan; Arıcan, Özer

doi:10.1186/s12575-015-0030-x

Cited by 22 publications

(28 citation statements)

References 33 publications

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“…By far, hydrolases were the most frequent class of enzymes isolated, probably because of the vast potential applications that this type of cold-active enzymes might have, due to their significant activities in diverse reactions and their potential catalysis of novel hydrolytic transformations (López-Iglesias and Gotor-Fernández, 2015 ). Lipases and esterases covered together 42% of the hydrolases from Table 1 , which is consistent with the worldwide use of lipases due to their features, as they are easy to handle, active in non-aqueous medium and are able to catalyze chemo-, regio-, and enantio-selective transformations (Kumar et al, 2016 ). The second largest class was oxidoreductases, but only with four representatives compared to the 84 hydrolases.…”

Section: Discussionsupporting

confidence: 72%

Discovery, Molecular Mechanisms, and Industrial Applications of Cold-Active Enzymes

et al. 2016

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Cold-active enzymes constitute an attractive resource for biotechnological applications. Their high catalytic activity at temperatures below 25 • C makes them excellent biocatalysts that eliminate the need of heating processes hampering the quality, sustainability, and cost-effectiveness of industrial production. Here we provide a review of the isolation and characterization of novel cold-active enzymes from microorganisms inhabiting different environments, including a revision of the latest techniques that have been used for accomplishing these paramount tasks. We address the progress made in the overexpression and purification of cold-adapted enzymes, the evolutionary and molecular basis of their high activity at low temperatures and the experimental and computational techniques used for their identification, along with protein engineering endeavors based on these observations to improve some of the properties of cold-adapted enzymes to better suit specific applications. We finally focus on examples of the evaluation of their potential use as biocatalysts under conditions that reproduce the challenges imposed by the use of solvents and additives in industrial processes and of the successful use of cold-adapted enzymes in biotechnological and industrial applications.

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Section: Discussionsupporting

confidence: 72%

Discovery, Molecular Mechanisms, and Industrial Applications of Cold-Active Enzymes

et al. 2016

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“…Arm homologies identified in Atlantic salmon, rainbow trout, and chinook salmon ( Table 2 ) with Arctic charr, were used to identify homeologous arm pairings within Arctic charr ( Table 4 ). Lower levels of duplicate marker regions were detected for certain arms, but can nonetheless be inferred based upon the recent extensive survey of duplicate gene copies in Atlantic salmon ( Hermansen et al 2016 ) ( Table 4 ). All seven homeologous pairs in Arctic charr identified as HRTAs in other species contain one chromosome arm that has undergone a chromosome fusion.…”

Section: Resultsmentioning

confidence: 98%

“… a Identified through their homologies in Atlantic salmon, and homeologies identified in Hermansen et al (2016) . …”

Section: Resultsmentioning

confidence: 99%

A SNP Based Linkage Map of the Arctic Charr (Salvelinus alpinus) Genome Provides Insights into the Diploidization Process After Whole Genome Duplication

Nugent

Easton

Norman

et al. 2017

G3 Genes|Genomes|Genetics

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Diploidization, which follows whole genome duplication events, does not occur evenly across the genome. In salmonid fishes, certain pairs of homeologous chromosomes preserve tetraploid loci in higher frequencies toward the telomeres due to residual tetrasomic inheritance. Research suggests this occurs only in homeologous pairs where one chromosome arm has undergone a fusion event. We present a linkage map for Arctic charr (Salvelinus alpinus), a salmonid species with relatively fewer chromosome fusions. Genotype by sequencing identified 19,418 SNPs, and a linkage map consisting of 4508 markers was constructed from a subset of high quality SNPs and microsatellite markers that were used to anchor the new map to previous versions. Both male- and female-specific linkage maps contained the expected number of 39 linkage groups. The chromosome type associated with each linkage group was determined, and 10 stable metacentric chromosomes were identified, along with a chromosome polymorphism involving the sex chromosome AC04. Two instances of a weak form of pseudolinkage were detected in the telomeric regions of homeologous chromosome arms in both female and male linkage maps. Chromosome arm homologies within the Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss) genomes were determined. Paralogous sequence variants (PSVs) were identified, and their comparative BLASTn hit locations showed that duplicate markers exist in higher numbers on seven pairs of homeologous arms, previously identified as preserving tetrasomy in salmonid species. Homeologous arm pairs where neither arm has been part of a fusion event in Arctic charr had fewer PSVs, suggesting faster diploidization rates in these regions.

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“…At present, measurement of F 2 -IsoPs is regarded as one of the most reliable approaches for the assessment of oxidative/nitrosative stress status or free-radical–mediated lipid peroxidation in vivo. The current data indicate that quantification of F 2 -IsoPs in either plasma or urine gives a highly precise and accurate index of oxidative/nitrosative stress [ 32 – 34 ]. Now, the biomarkers of oxidative/nitrosative stress/damage and the methods used to measure them to determine an individual’s oxidative status in relation to disease conditions frequently vary among studies, making comparisons of study findings difficult.…”

Section: Oxidative/nitrosative Stressmentioning

confidence: 99%

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state

Kurutaş

2015

Nutr J

Self Cite

1,656

933

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Remarkable interest has risen in the idea that oxidative/nitrosative stress is mediated in the etiology of numerous human diseases. Oxidative/Nitrosative stress is the result of an disequilibrium in oxidant/antioxidant which reveals from continuous increase of Reactive Oxygen and Reactive Nitrogen Species production. The aim of this review is to emphasize with current information the importance of antioxidants which play the role in cellular responce against oxidative/nitrosative stress, which would be helpful in enhancing the knowledge of any biochemist, pathophysiologist, or medical personnel regarding this important issue. Products of lipid peroxidation have commonly been used as biomarkers of oxidative/nitrosative stress damage. Lipid peroxidation generates a variety of relatively stable decomposition end products, mainly α, β-unsaturated reactive aldehydes, such as malondialdehyde, 4-hydroxy-2-nonenal, 2-propenal (acrolein) and isoprostanes, which can be measured in plasma and urine as an indirect index of oxidative/nitrosative stress. Antioxidants are exogenous or endogenous molecules that mitigate any form of oxidative/nitrosative stress or its consequences. They may act from directly scavenging free radicals to increasing antioxidative defences. Antioxidant deficiencies can develop as a result of decreased antioxidant intake, synthesis of endogenous enzymes or increased antioxidant utilization. Antioxidant supplementation has become an increasingly popular practice to maintain optimal body function. However, antoxidants exhibit pro-oxidant activity depending on the specific set of conditions. Of particular importance are their dosage and redox conditions in the cell.

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Evaluation of local trace element status and 8-Iso-prostaglandin F2α concentrations in patients with Tinea pedis

Cited by 22 publications

References 33 publications

Discovery, Molecular Mechanisms, and Industrial Applications of Cold-Active Enzymes

Discovery, Molecular Mechanisms, and Industrial Applications of Cold-Active Enzymes

A SNP Based Linkage Map of the Arctic Charr (Salvelinus alpinus) Genome Provides Insights into the Diploidization Process After Whole Genome Duplication

The importance of antioxidants which play the role in cellular response against oxidative/nitrosative stress: current state

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