Evaluation of metabolic changes within the normal appearing gray and white matters in neurologically asymptomatic HIV-1-positive and HCV-positive patients: Magnetic resonance spectroscopy and immunologic correlation

Bladowska, Joanna; Zimny, Anna; Kołtowska, Anna; Szewczyk, P.; Knysz, Brygida; Gąsiorowski, Jacek; Furdal, Michał; Sąsiadek, Marek

doi:10.1016/j.ejrad.2012.11.029

Cited by 39 publications

(43 citation statements)

References 29 publications

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“…VTQ can reflect the change of elasticity quantitatively in malignant nodules. The mean SWV value of malignant thyroid nodules was significantly higher than that of normal tissue or benign nodules [10, 12, 21–23]. In this study, similar results were found in nodules <1 cm.…”

Section: Discussionsupporting

confidence: 85%

“…The median of all 7 measurements per lesion was calculated and used for further analysis. The value of “x.xx m/s” was allocated to be 9 m/s after excluding the possible influencing factors such as patient's respiration or motion and operator's inappropriate gesture [12], because all the nodules included in the study were solid or almost solid; thus, “x.xx m/s” was not allocated to be 0 m/s (i.e., corresponding cystic portion).…”

Section: Methodsmentioning

confidence: 99%

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Acoustic Radiation Force Impulse Imaging: A New Tool for the Diagnosis of Papillary Thyroid Microcarcinoma

Zhang

Liu

et al. 2014

BioMed Research International

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Purpose. To evaluate the diagnostic performance of ARFI imaging in differentiating between benign and malignant thyroid nodules <1 cm. Materials and Methods. 173 pathologically proven thyroid nodules (77 benign, 96 malignant) in 157 patients were included in this study. Receiver-operating characteristic curve (ROC) analyses were performed to assess the diagnostic performance of conventional ultrasound (US) and ARFI imaging in papillary thyroid microcarcinoma (PTMC). The independent risk factors for predicting PTMC were evaluated. Results. The mean SWV value of benign and malignant thyroid nodules were 2.57 ± 0.79 m/s (range: 0.90–4.92 m/s) and 3.88 ± 2.24 m/s (range: 1.49–9.00 m/s) (P = 0.000). Az for VTI elastography score was higher than that for hypoechoic, absence of halo sign, and type III vascularity (P < 0.05). The optimal cut-offs for VTI elastography score and SWV were score 4 and 3.10 m/s. Gender, hypoechoic, taller than wide, VTI elastography score ≥ 4, and SWV > 3.10 m/s had been found to be independent risk factors for predicting PTMC. Conclusion. ARFI elastography can provide elasticity information of PTMC quantitatively (VTQ) and directly reflects the overall elastic properties (VTI). Gender, hypoechogenicity, taller than wide, VTI elastography score ≥ 4, and SWV > 3.10 m/s are independent risk factors for predicting PTMC. ARFI elastography seems to be a new tool for the diagnosis of PTMC.

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Section: Discussionsupporting

confidence: 85%

Section: Methodsmentioning

confidence: 99%

Acoustic Radiation Force Impulse Imaging: A New Tool for the Diagnosis of Papillary Thyroid Microcarcinoma

Zhang

Liu

et al. 2014

BioMed Research International

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“…Although they are in the asymptomatic stage, their nervous system may have been attacked by HIV. Some scholars 6,14,[19][20][21] indicated that central nervous system has been involved in the course of HIV infection in the early stage of the disease. We hope to identify the damaged parts of the nervous system and make a prediction of opportunistic infections by analyzing apparent diffusion coefficient (ADC), distribution diffusion coefficient (DDC) and heterogeneity index (a) values.…”

Section: Introductionmentioning

confidence: 99%

“…Moreover, asymptomatic HIV infection, a group which is often neglected, is hardly taken into consideration in scientific research. 6,9,14,19 In this study, asymptomatic HIV-positive adolescent orphans, who were born with HIV owing to mother-to-child transmission, were scanned using DWI with multi-b-value. The immune system of infants was immature and immune system function was poor.…”

Section: Introductionmentioning

confidence: 99%

“…Bladowska found that the relative blood volume values of HIV-infected persons were significantly lower than those of healthy controls in the right side of the temporal-parietal cortex and the left side of prefrontal cortex. 6,14 All of the HIV-infected persons had no mental illness, brain opportunistic infections and intracranial tumours, and no definite changes in brain structure and abnormal signal exists in conventional MRI examination. They thought that PWI could reflect changes in unilateral brain regions before HIV induces neurocognitive disorders.…”

mentioning

confidence: 99%

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Application of brain multi-b-value diffusion-weighted imaging (DWI) in adolescent orphans from AIDS families

Jiang

Zhong

Zhou

et al. 2016

BJR

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Objective: To evaluate the application value of multib-value diffusion-weighted imaging (DWI) with monoexponential model and stretched-exponential model in the diagnosis of HIV-positive patients. Methods: 50, 150, 200, 400, 600, 800 s mm 22) DWI was performed in 23 adolescent orphans from AIDS families, including 15 HIV-positive subjects and 8 HIV-negative healthy subjects. Apparent diffusion coefficient (ADC) values were fitted by monoexponential model; distribution diffusion coefficient (DDC) values and heterogeneity index (a) values were fitted by stretched-exponential model in bilateral basal ganglia, then non-parametric tests were performed. Results: The signal intensity attenuation in multi-b-value DWI could be well described by both mono-exponential model and stretched-exponential model. In the left basal ganglia, mean a-values in HIV-positive subjects (a 5 0.848 6 0.068) were significantly lower than that in healthy subjects (a 5 0.923 6 0.050, p 5 0.013). There was no statistical difference of a-values between HIV-positive subjects and healthy control subjects in the right basal ganglia. Apart from these, there were also no statistical differences of DDC values or ADC values between two groups in bilateral basal ganglia (all p . , we can see stretched-exponential model DWI can provide more information than mono-exponential model DWI. Advances in knowledge: Multi-b-value DWI was performed in subjects with HIV. DWI measurements could be neuroimaging biomarkers of cerebral injury in the course of HIV infection.

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Neuroimaging Advances in Diagnosis and Differentiation of HIV, Comorbidities, and Aging in the cART Era

Nir

Haddad

Thompson

et al. 2021

Neurocognitive Complications of HIV-Infection

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Evaluation of metabolic changes within the normal appearing gray and white matters in neurologically asymptomatic HIV-1-positive and HCV-positive patients: Magnetic resonance spectroscopy and immunologic correlation

Cited by 39 publications

References 29 publications

Acoustic Radiation Force Impulse Imaging: A New Tool for the Diagnosis of Papillary Thyroid Microcarcinoma

Acoustic Radiation Force Impulse Imaging: A New Tool for the Diagnosis of Papillary Thyroid Microcarcinoma

Application of brain multi-b-value diffusion-weighted imaging (DWI) in adolescent orphans from AIDS families

Neuroimaging Advances in Diagnosis and Differentiation of HIV, Comorbidities, and Aging in the cART Era

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