Evaluation of multi-microbe probiotics prepared by submerged liquid or solid substrate fermentation and antibiotics in weaning pigs

Bacteriophage cocktail and multi-strain probiotics in the feed for weanling pigs: effects on intestine morphology and targeted intestinal coliforms and Clostridium

“…In recent years, considerable efforts have been made for developing novel non-antibiotic feed additives which have the potential to improve the gut health, immunity and performance of pigs (Jin et al, 2009;Choi et al, 2011b;Yoon et al, 2012 and. Among various alternatives, bacteriophages have received attention due to their natural antimicrobial properties and lower propensity for the development of bacterial resistance (Gebru et al, 2010;Wittebole et al, 2014;Kim et al 2014b).…”

“…Recently, it has been reported that supplementation with bacteriophages resulted in improved growth performance and gut health of growing pigs (Yan et al, 2012;Kim et al 2014b). Previous studies in the author's laboratory reported that the multimicrobial probiotic products had potential to improve the performance and gut health, and could be used as an alternative to antibiotic growth promoters in pigs and broilers (Choi et al, 2011b;Kim et al, 2012). Therefore, the present study was designed to investigate the effects of dietary supplementation with bacteriophage and also its combination with fermented probiotic product on growth performance, nutrient digestibility, intestinal and fecal microbiota and intestinal morphology of weanling pigs.…”

Inoculated fermented corn as dietary performance and health enhancer in pigs: literature and in vitro study

“…Lactobacillus acidophilus was of porcine origin, Bacillus subtilis was isolated from natto (fermented soy bean), Saccharomyces cerevisiae and Aspergillus oryzae were isolated from koji (malted wheat). The results indicated that multi-microbe probiotics prepared by SF method were superior to probiotics prepared by LF in improving growth performance and being beneficial to gut microflora and reducing harmful gut microflora in weaning pigs (Choi et al 2011).…”

“…Taken together, the multi-microbe probiotics approach of Choi et al (2011) may result in the best chance to improve pig performance and health by feeding pigs a diet partly consisting of inoculated fermented chopped corn. A corn specific Lactobacillus amylophilus GV6 (Vishnu et al 2002) may be used in combination with one or more pig specific probiotics like Lactobacillus acidophilus, Lactobacillus salivarius, Lactobacillus reuteri, Lactobacillus plantarum and Lactobacillus johnsonii depending on the availability of these strains.…”

“…Commercially available pig probiotics may be used as alternative source of inoculation, if no restrictions to the use apply. An inoculation level of 0.2-0.3% to the fermentable substrate seems optimal (Yang et al 2006, Choi et al 2011). …”