Evaluation of nasal symptoms and mucociliary function in patients with allergic rhinitis treated with chemosurgery using trichloroacetic acid

Tuna, Evrim E. Ünsal; Özbek, Cem; Koç, Can; Özdem, Cafer

doi:10.1016/j.amjoto.2006.12.006

Cited by 9 publications

(3 citation statements)

References 16 publications

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“…TCA is frequently used for endoscopic chemocauterization, and TCA‐based chemocauterization is reported to result in high rates of obliteration. TCA is also commonly used for chemical skin peeling and treating skin pigmentation, genital warts, and allergic rhinitis . The mechanism by which TCA affects the skin and mucosa involves the immediate coagulation of dermal protein and the induction of marked vasoconstriction after the coagulation procedure.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic chemocauterization for pyriform sinus fistula in children

Yanagisawa

Oshio

Kato

et al. 2017

Pediatrics International

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Section: Discussionmentioning

confidence: 99%

Endoscopic chemocauterization for pyriform sinus fistula in children

Yanagisawa

Oshio

Kato

et al. 2017

Pediatrics International

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“…Vidian neurectomy15, turbinectomy, electrocautery, cryosurgery, chemosurgery16, microwave, laser17 and radiofrequency18 are most commonly-used surgical treatments for AR. These treatments are proved to be effective while dry eyes, nasal bleeding, crusting, and synechia are often found postoperatively.…”

Section: Discussionmentioning

confidence: 99%

Higher Dosage of HIFU Treatment May Lead to Higher and Longer Efficacy for Moderate to Severe Perennial Allergic Rhinitis

Wei¹,

Zhang²,

Shi³

et al. 2013

Int. J. Med. Sci.

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Objectives: This study was to compare the efficacies and side effects of high intensity focused ultrasound (HIFU) treatment for perennial allergic rhinitis (PAR) with regular and increased dosage.Study design: A prospectively assembled cohort was retrospectively analyzed through visual analogue scale (VAS).Methods: Regular dosage of HIFU treatment was applied to 56 PAR patients in group A. An increased dosage as twice as the regular one was applied to 48 patients in group B. Nasal obstruction, sneezing, rhinorrhea and rhinocnesmus, which were recognized as the four main symptoms of allergic rhinitis (AR), were evaluated before treatment, 3 months after treatment, and 1 year after treatment. The satisfaction of patients was also evaluated at 1 year postoperatively. Biopsy of the inferior turbinate and morphometric analysis were applied to 11 patients in group A and 10 in group B before HIFU treatment and 3 months after treatment.Results: Comparing the AR symptoms before treatment, There is no statistical difference observed between group A and B (p>0.05). The four main symptoms at 3 months and 1 year after treatment were all significantly improved (p<0.01) in both group A and B. The VAS scores of AR symptoms in Group B were lower than those in Group A at the same stage after treatment, especially at 1 year after treatment (p<0.05). Comparing the results at 3 months and 1 year after treatment, a tendency of recurrence of these symptoms was observed statistically in group A (p<0.05), but not in group B (p>0.05). More cases of nasal dryness and perirhinal swelling were found in group B than those in group A (p<0.05), while all side effects were mild and temporary. Patients in group B were more satisfied than those in group A (p=0.0866 >0.05), though not statistically significant. More reduction of the eosinophils, other inflammatory cells, and the submucosal glands was observed after HIFU treatment in group B than that in group A (p<0.05).Conclusions: A proper increment of HIFU dosage may be recommended to meet the needs of more improvement of AR symptoms and less recurrence.

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“…In 1926, Denker and Kahler described the use of trichloroacetic acid [36] (TCA) solution to the inferior turbinate in the hypertrophic rhinitis. The effect of TCA consists in protein degeneration [37]. This action on turbinate mucosa is aggressive and damages the mucociliary function.…”

Section: Chemosurgerymentioning

confidence: 99%

Turbinate Surgery in Chronic Rhinosinusitis: Techniques and Ultrastructural Outcomes

Neri¹,

Cazzato²,

Vestrini³

et al. 2019

Rhinosinusitis

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Chronic nasal obstruction due to hypertrophic rhinitis is commonly associated with perennial allergic and nonallergic rhinitis. It is not a simple enlargement of mucosal and submucosal tissues, but it is characterized by deep histological modifications. This pathology, a very frequent condition encountered in rhinological practice, has a significant impact on quality of life. Patients usually complain about sneezing, rhinorrhea, frontal headache, postnasal drip, snoring, blocked nasal ducts, and sleep disorders. When medical therapy fails, surgical reduction of inferior turbinates is mandatory. A large variety of surgical techniques in literature exist, but there is a lack of consensus about which is the proper technique to perform. In this chapter, we describe the most important techniques of inferior turbinate reduction with advantages and disadvantages of each one.

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Evaluation of nasal symptoms and mucociliary function in patients with allergic rhinitis treated with chemosurgery using trichloroacetic acid

Cited by 9 publications

References 16 publications

Endoscopic chemocauterization for pyriform sinus fistula in children

Endoscopic chemocauterization for pyriform sinus fistula in children

Higher Dosage of HIFU Treatment May Lead to Higher and Longer Efficacy for Moderate to Severe Perennial Allergic Rhinitis

Turbinate Surgery in Chronic Rhinosinusitis: Techniques and Ultrastructural Outcomes

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