Evaluation of Right Ventricular Function

Greyson, Clifford R.

doi:10.1007/s11886-011-0174-5

Cited by 29 publications

(25 citation statements)

References 49 publications

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“…The PET imaging was performed with GE Advance PET/CT scanner (General Electric Medical System, Milwaukee, WI). RVFFAU was studied at the fasted state using 14 (5,17). PET image raw files were corrected for attenuation, dead time, and decay.…”

Section: Methodsmentioning

confidence: 99%

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Right ventricular metabolic adaptations to high-intensity interval and moderate-intensity continuous training in healthy middle-aged men

Heiskanen

Leskinen

Heinonen

et al. 2016

American Journal of Physiology-Heart and Circulatory Physiology

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Heiskanen MA, Leskinen T, Heinonen IH, Löyttyniemi E, Eskelinen JJ, Virtanen K, Hannukainen JC, Kalliokoski KK. Right ventricular metabolic adaptations to high-intensity interval and moderate-intensity continuous training in healthy middle-aged men. Am J Physiol Heart Circ Physiol 311: H667-H675, 2016. First published July 22, 2016; doi:10.1152/ajpheart.00399.2016Despite the recent studies on structural and functional adaptations of the right ventricle (RV) to exercise training, adaptations of its metabolism remain unknown. We investigated the effects of short-term, high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on RV glucose and fat metabolism. Twenty-eight untrained, healthy 40 -55 yr-old-men were randomized into HIIT (n ϭ 14) and MICT (n ϭ 14) groups. Subjects performed six supervised cycle ergometer training sessions within 2 wk (HIIT session: 4 -6 ϫ 30 s all-out cycling/4-min recovery; MICT session: 40 -60 min at 60% peak O 2 uptake). Primary outcomes were insulin-stimulated RV glucose uptake (RVGU) and fasted state RV free fatty acid uptake (RVFFAU) measured by positron emission tomography. Secondary outcomes were changes in RV structure and function, determined by cardiac magnetic resonance. RVGU decreased after training (Ϫ22% HIIT, Ϫ12% MICT, P ϭ 0.002 for training effect), but RVFFAU was not affected by the training (P ϭ 0.74). RV end-diastolic and endsystolic volumes, respectively, increased ϩ5 and ϩ7% for HIIT and ϩ4 and ϩ8% for MICT (P ϭ 0.002 and 0.005 for training effects, respectively), but ejection fraction mildly decreased (Ϫ2% HIIT, Ϫ4% MICT, P ϭ 0.034 for training effect). RV mass and stroke volume remained unaltered. None of the observed changes differed between the training groups (P Ͼ 0.12 for group ϫ training interaction). Only 2 wk of physical training in previously sedentary subjects induce changes in RV glucose metabolism, volumes, and ejection fraction, which precede exercise-induced hypertrophy of RV.Listen to this article's corresponding podcast at http://ajpheart.podbean. com/e/right-ventricular-metabolic-adaptations-to-exercise-training/. EXERCISE-INDUCED HYPERTROPHY of the left ventricle (LV), socalled athlete's heart, is generally associated with excellent health outcomes. Right ventricle (RV) has remained less studied, and for a long time it was considered merely as "a passive conduit" (8,14,42). Recently, RV adaptations to exercise training have gained increased research interest. While previous studies concerning the effects of training on the RV have reported balanced hypertrophy with the LV (21, 35-37), other studies have reported RV dysfunction following intense endurance exercise (3,9,10,25,26,40). A recent meta-analysis further confirmed that prolonged intense exercise leads to reduction of RV function, while LV function remains unaffected (6), underlining the need for further studies specifically on RV adaptations.As an alternative for traditional moderate-intensity continuous training (MICT), high-intensity interval training (H...

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Section: Methodsmentioning

confidence: 99%

“…EXERCISE-INDUCED HYPERTROPHY of the left ventricle (LV), socalled athlete's heart, is generally associated with excellent health outcomes. Right ventricle (RV) has remained less studied, and for a long time it was considered merely as "a passive conduit" (8,14,42). Recently, RV adaptations to exercise training have gained increased research interest.…”

mentioning

confidence: 99%

Right ventricular metabolic adaptations to high-intensity interval and moderate-intensity continuous training in healthy middle-aged men

Heiskanen

Leskinen

Heinonen

et al. 2016

American Journal of Physiology-Heart and Circulatory Physiology

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“…It enables accurate quantification of heart chambers volumes and calculation of myocardial mass from tracing epicardial and endocardial borders and multiplying them by myocardial density [54]. Valvular regurgitant volumes and shunt severity can also be precisely calculated using velocity-encoded cine images [55].…”

Section: Imaging and Assessment Of Right Ventricular Structure And Fumentioning

confidence: 99%

The right ventricle in patients with chronic heart failure and atrial fibrillation

Majos

Dąbrowski²,

Szwed³

2013

Cardiol J

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“…Historically, percutaneous mechanical support for RVF has been limited to the IABP, which only indirectly benefits RV function by reducing LV afterload and enhancing coronary perfusion. Since RV stroke work requires one-sixth the energy expenditure of the LV [68], pumps that generate continuous flow with a minimal, low-amplitude pulsatile component, may more closely approximate native RV function.…”

Section: Right-sided Supportmentioning

confidence: 99%

2015 SCAI/ACC/HFSA/STS clinical expert consensus statement on the use of percutaneous mechanical circulatory support devices in cardiovascular care (Endorsed by the American heart assocation, the cardiological society of India, and sociedad latino Americana de cardiologia intervencion; Affirmation of value by the canadian association of interventional cardiology–association canadienne de cardiologie d'intervention)

Rihal

Naidu

Givertz

et al. 2015

Cathet Cardio Intervent

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Although historically the intra-aortic balloon pump has been the only mechanical circulatory support device available to clinicians, a number of new devices have become commercially available and have entered clinical practice. These include axial flow pumps, such as Impella V R ; left atrial to femoral artery bypass pumps, specifically the is approached by other guideline developers and asked to review and consider guidelines for endorsement. Guidelines developed by external organizations will be considered for affirmation of value. The CAIC may not agree with every recommendation in such a document, but overall considers the document to be of educational value to its members. Catheterization and Cardiovascular Interventions 85:E175-E196 (2015)TandemHeart; and new devices for institution of extracorporeal membrane oxygenation. These devices differ significantly in their hemodynamic effects, insertion, monitoring, and clinical applicability. This document reviews the physiologic impact on the circulation of these devices and their use in specific clinical situations. These situations include patients undergoing high-risk percutaneous coronary intervention, those presenting with cardiogenic shock, and acute decompensated heart failure. Specialized uses for rightsided support and in pediatric populations are discussed and the clinical utility of mechanical circulatory support devices is reviewed, as are the American College of Cardiology/American Heart Association clinical practice guidelines.

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Evaluation of Right Ventricular Function

Cited by 29 publications

References 49 publications

Right ventricular metabolic adaptations to high-intensity interval and moderate-intensity continuous training in healthy middle-aged men

Right ventricular metabolic adaptations to high-intensity interval and moderate-intensity continuous training in healthy middle-aged men

The right ventricle in patients with chronic heart failure and atrial fibrillation

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