Evaluation of Short-Term Side Effects Following the First Dose of COVID-19 Vaccines Among Physicians and Dentists: A Cross-Sectional Study from India

Majumder, Anwarul Azim; Singh, Keerti; Johnson, Wms; Rajasundaram, Archana; Gupta, Subir; Gaur, Uma; Kumar, Santosh; Chatterjee, Madhuri; Rabbi, Ahbab Mohammad Fazle; Sangishetti, Vijay Prasad; Rahman, Sayeeda; Campbell, Michael H.; Harewood, Heather; Bharatha, Ambadasu; Krishnamurthy, Kandamaran; Kabir, Russell; Parsa, Ali Davod; Mohammmad, Shegufta; Haque, Mainul

doi:10.2147/jmdh.s390364

Cited by 7 publications

(11 citation statements)

References 46 publications

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“…We investigated the prevalence, onset, duration, and severity of self-reported side effects among students, most of whom (95%) had received Covishield vaccines. In two studies conducted in India and Bangladesh, the percentages of participants who received Covishield vaccines were 91% ( Majumder et al., 2023 ) and 100%, ( Majumder et al., 2022 ) respectively. In the present study, less than half (45.3%) of respondents reported one or more vaccine-related side effects after first doses of Covishield vaccines.…”

Section: Discussionmentioning

confidence: 99%

“…The survey used an instrument designed and employed by the research team in two previous studies ( Majumder et al, 2022 ; Majumder et al, 2023 ). After validation, the questionnaire was administered using non-probability sampling between 26th April 2021 and 26th May 2021 and was distributed via Google Forms to students of six medical and dental colleges and teaching hospitals in four states (Tamil Nadu, Madhya Pradesh, Gujarat and West Bengal) of India.…”

Section: Methodsmentioning

confidence: 99%

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Self-reported side effects of COVID-19 vaccines among health professions students in India

Majumder,

Bharatha,

Kumar

et al. 2024

PeerJ

Self Cite

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Studies focusing on the safety and common side effects of vaccines play a crucial role in enhancing public acceptance of vaccination. Research is scarce regarding the usage of COVID-19 vaccines and the side effects experienced by health professions students in India and other countries. This study aimed to document self-reported side effects associated with COVID-19 vaccination among medical and dental students of six medical and dental colleges and teaching hospitals in four states (Tamil Nadu, Madhya Pradesh, Gujarat, and West Bengal) of India. A cross-sectional survey using purposive sampling of medical and dental students was conducted from 26 April to 26 May 2021. Data was collected using a Google Forms questionnaire capturing information regarding receiving COVID-19 vaccines, side effects and symptoms, onset and duration of symptoms, use of treatment to alleviate symptoms, awareness of haematologic risks associated with vaccination, and side effects from previous (non-COVID-19) vaccinations. The majority (94.5%) of participants received both doses of the Covishield/AstraZeneca COVID-19 vaccine. Among participants (n = 492), 45.3% (n = 223) reported one or more side effects. The most frequently reported side effects were soreness of the injected arm (80.3%), tiredness (78.5%), fever (71.3%), headache (64.1%), and hypersomnia (58.7%). The two most common severe symptoms were fever (14.8%) and headache (13%). Most side effects appeared on the day of vaccination: soreness of the injection site (57%), fever (43.1%), and tiredness (42.6%). Most reported symptoms persisted for one to three days–soreness of the injection site (53%), fever (47.1%), and headache (42.6%). Logistic regression showed that women were almost 85% less likely to report side effects. The study’s findings corroborate the safety of the Covishield/AstraZeneca vaccine’s first dose, evidenced by the relatively minor and transient nature of the side effects. However, the study underscores the necessity for ongoing research to assess the long-term impacts of COVID-19 vaccines, especially in the context of booster doses, thereby contributing to the global understanding of vaccine safety and efficacy.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Self-reported side effects of COVID-19 vaccines among health professions students in India

Majumder,

Bharatha,

Kumar

et al. 2024

PeerJ

Self Cite

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show abstract

“…The Covishield vaccine (AstraZeneca) was administered to more than 91% of the responders, and the most frequent side effects were pain at the injection site, followed by the tenderness of the administered arm (78.9%), fatigue (71.1%), fever (54.9%), and headaches (49.8%). The majority of the early immunization-related symptoms were minor and were gone within three days [ 23 ]. Similar to this, studies conducted in India found a prevalence of adverse effects among healthcare workers ranging from 40-70% [ 24 - 26 ].…”

Section: Discussionmentioning

confidence: 99%

Side Effects of COVID-19 Vaccines Among Diabetic Subjects and Healthy Individuals

Khan¹,

Khan²,

Zaman³

et al. 2023

Cureus

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Objectives Vaccinations protect against disease through various ways, but the process of developing immunity might result in side effects. This study determined the immediate side effects of coronavirus disease 2019 (COVID-19) vaccination among patients with diabetes and non-diabetic participants. Methods This multi-center, cross-sectional study was conducted in multiple hospitals in Karachi, Pakistan. The duration of the study was six months, from March 1, 2022, to August 31, 2022. A total of 1150 participants who received one of the COVID-19 vaccines, for instance, Sinopharm, AstraZeneca, Sinovac, and Pfizer (double or booster doses) were included in the study and allocated into two groups: diabetics (n=540) and non-diabetics (n=610). The chi-square test was used to compare the frequency of side effects between diabetic and non-diabetic participants. The association between means of demographic variables such as age and weight was compared using an independent t-test. Results The study findings showed that the mean age of the group with diabetes was 46.73±14.98 years and that of the non-diabetic group was 44.01±14.80 years with a significant difference between them (p=0.002). The majority of participants, 187 (34.6%) patients with diabetes received Pfizer, while 234 (38.4%) non-diabetic participants received Sinovac. Following the first dose, side effects were higher in patients with diabetes. Burning at the injection site, fever, and pain were the most commonly reported side effects in patients with diabetes following the first dose. Additionally, following the second dose, burning at the injection site, muscular pain, fever, and pain were the most commonly observed side effects, with a significant association among diabetic and non-diabetic participants (p<0.001). Conclusion Diabetes is a prevalent comorbidity in individuals infected with COVID-19, and patients with diabetes report more side effects from immunization than non-diabetic participants. The most commonly reported side effects of the vaccine in diabetic participants were observed to be burning at the injection site, fever, muscle and joint pain, and swelling at the injection site. Additionally, participants with and without diabetes reported feeling satisfied with their vaccines.

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“…Addressing health-related concerns about COVID-19 vaccines is of utmost importance and requires healthcare providers to furnish credible and evidence-based information on vaccine safety and efficacy, in addition to closely monitoring and reporting any adverse events. Given that adverse events associated with COVID-19 vaccines are mostly mild and resolvable [48] , healthcare providers must help patients to understand this concept and stay informed.…”

Section: Discussionmentioning

confidence: 99%

Global acceptance of COVID-19 vaccine among persons with diabetes: A systematic review and meta-analysis

Ekpor

Akyirem

2023

Diabetes Research and Clinical Practice

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Evaluation of Short-Term Side Effects Following the First Dose of COVID-19 Vaccines Among Physicians and Dentists: A Cross-Sectional Study from India

Cited by 7 publications

References 46 publications

Self-reported side effects of COVID-19 vaccines among health professions students in India

Self-reported side effects of COVID-19 vaccines among health professions students in India

Side Effects of COVID-19 Vaccines Among Diabetic Subjects and Healthy Individuals

Global acceptance of COVID-19 vaccine among persons with diabetes: A systematic review and meta-analysis

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