Evaluation of Systemic Antioxidant Level and Oxidative Stress In Relation to Lifestyle and Disease Progression in Asthmatic Patients/ Evaluacija nivoa antioksidanasa i oksidativnog stresa u sistemu u odnosu na životni stil i progresiju bolesti kod obolelih od astme

Yadav, Abhay Singh; Saini, Manisha

doi:10.1515/jomb-2015-0006

Cited by 17 publications

(7 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…ROS reaction with various biomolecules such as proteins, lipids, and DNA may cause cell injury, leading to apoptosis and necrosis [ 28 , 65 , 66 ]. Serum concentrations of antioxidants have been shown to correlate positively with FEV 1 in patients with COPD, and supplementation with antioxidants such as vitamin C improves the symptoms of the disease [ 64 , 67 , 68 ].…”

Section: Discussionmentioning

confidence: 99%

The Effectiveness of Supplementation with Key Vitamins, Minerals, Antioxidants and Specific Nutritional Supplements in COPD—A Review

et al. 2023

View full text Add to dashboard Cite

Currently, an increasing amount of evidence supports the notion that vitamins C, D and E, carotenoids, and omega-3 fatty acids may protect against the progression of chronic respiratory diseases. Although chronic obstructive pulmonary disease (COPD) primarily affects the lung, it is often accompanied by extrapulmonary manifestations such as weight loss and malnutrition, skeletal muscle dysfunction, and an excess of harmful oxidants, which can lead to a decline in quality of life and possible death. Recently, the role of various vitamins, minerals, and antioxidants in mitigating the effects of environmental pollution and smoking has received significant attention. Therefore, this review evaluates the most relevant and up-to-date evidence on this topic. We conducted a literature review between 15 May 2018 and 15 May 2023, using the electronic database PubMed. Our search keywords included COPD, chronic obstructive pulmonary disease, FEV1, supplementation: vitamin A, vitamin D, vitamin E, vitamin C, vitamin B, omega-3, minerals, antioxidants, specific nutrient supplementations, clinical trials, and randomized controlled trials (RCTs). We focused on studies that measured the serum levels of vitamins, as these are a more objective measure than patient self-reports. Our findings suggest that the role of appropriate dietary supplements needs to be reconsidered for individuals who are predisposed to or at risk of these conditions.

show abstract

Section: Discussionmentioning

confidence: 99%

The Effectiveness of Supplementation with Key Vitamins, Minerals, Antioxidants and Specific Nutritional Supplements in COPD—A Review

et al. 2023

View full text Add to dashboard Cite

show abstract

“…This neuropathy is suspected to occur due to activation of latent HVS viral infection or an autoimmune reaction. However, the exact events leading to this inflammation remain unknown ( 3 , 5 , 8 , 15 ). It is likely that the increased OS levels observed herein may play a role in the development of BP.…”

Section: Discussionmentioning

confidence: 99%

Oxidative Stress and Antioxidant Status in Patients with Bell’s Palsy

Terzi¹,

Dursun²,

Yılmaz³

et al. 2017

Journal of Medical Biochemistry

View full text Add to dashboard Cite

SummaryBackgroundBell's palsy (BP) is the most common acute mononeuropathy of unilateral facial paralysis. Immune, infective and ischaemic mechanisms are potential contributors to the development of BP, but the precise cause remains unclear. Recently, oxidative stress has been proposed as a risk factor of various idiopathic diseases. The aim of this study was to investigate the possible role of oxidative stress in patients with BP.MethodsThirty-two patients with BP and 30 healthy controls were included in this study. Serum total oxidant status (TOS), total antioxidant status (TAS) and oxidative stress index (OSI) were measured by the Erel method.ResultsSerum TOS activities and OSI values were significantly higher in patients with BP compared with the control group (P <0.003 for all comparisons), whereas there was no significant difference between the groups in terms of TAS levels (P >0.05).ConclusionsThe data suggest that oxidative stress is increased in BP. These results of high oxidative stress in patients with BP may be helpful to clarify the etiopathogenesis of BP and contribute to improvement in the management or prevention of the disease.

show abstract

“…Asthmatic current smokers showed increased serum levels of malondialdehyde (MDA) and decreased levels of the ferric-reducing ability of plasma (FRAP) [ 37 ]. Higher MDA levels in exhaled breath condensate (EBC) have been reported in active smoking asthmatics than in their ex-smoking and nonsmoking counterparts [ 38 ].…”

Section: Biomarkers Of Os and Inflammation In Relation To Smoking Statusmentioning

confidence: 99%

Antioxidant Intake and Biomarkers of Asthma in Relation to Smoking Status—A Review

Alsharairi

2023

CIMB

View full text Add to dashboard Cite

Asthma is considered a chronic inflammatory disorder associated with airway hyperresponsiveness (AHR). Increased oxidative stress (OS) is a clinical feature of asthma, which promotes the inflammatory responses in bronchial/airway epithelial cells. Smokers and nonsmokers with asthma have been shown to have increases in several OS and inflammatory biomarkers. However, studies suggest significant differences in OS and inflammation biomarkers between smokers and nonsmokers. A few studies suggest associations between antioxidant intake from diet/supplements and asthma in patients with different smoking status. Evidence is lacking on the protective role of antioxidant vitamin and/or mineral consumption against asthma by smoking status with respect to inflammation and OS biomarkers. Therefore, the aim of this review is to highlight current knowledge regarding the relations between antioxidant intake, asthma, and its associated biomarkers, according to smoking status. This paper can be used to guide future research directions towards the health consequences of antioxidant intake in smoking and nonsmoking asthmatics.

show abstract

Evaluation of Systemic Antioxidant Level and Oxidative Stress In Relation to Lifestyle and Disease Progression in Asthmatic Patients/ Evaluacija nivoa antioksidanasa i oksidativnog stresa u sistemu u odnosu na životni stil i progresiju bolesti kod obolelih od astme

Cited by 17 publications

References 27 publications

The Effectiveness of Supplementation with Key Vitamins, Minerals, Antioxidants and Specific Nutritional Supplements in COPD—A Review

The Effectiveness of Supplementation with Key Vitamins, Minerals, Antioxidants and Specific Nutritional Supplements in COPD—A Review

Oxidative Stress and Antioxidant Status in Patients with Bell’s Palsy

Antioxidant Intake and Biomarkers of Asthma in Relation to Smoking Status—A Review

Contact Info

Product

Resources

About