Evaluation of the Activities of Antimicrobial Agents on Multi-drug Resistant Gram Positive Bacteria Isolated from Intensive Care Units

Karameşe, Murat

doi:10.15226/sojmid.2013.00113

Cited by 1 publication

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“…NI develops in up to 24% of the pediatric ICU patients [ 4 ]. Furthermore, NIs are responsible for 30–88% of deaths in these patients [ 5 , 6 ]. Scientific studies have stated that pediatric intensive care unit (PICU) patients with a TBI are at high risk for the development of NIs [ 7 , 8 ] and have multiple risk factors, including invasive devices, mechanical ventilation, and immunosuppressive medications due to disruptions in tissue integrity, and impaired host defense mechanisms [ 9 – 11 ].…”

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confidence: 99%

Risk factors and cost of nosocomial infections in pediatric patients with traumatic brain injury

Incekoy Girgin

2023

North Clin Istanbul

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OBJECTIVE This study aimed to determine the factors that increase nosocomial infections (NIs) in pediatric patients with traumatic brain injury (TBI) and the effects on both treatment cost and length of hospital stay. METHODS We performed a case-control study on patients admitted to the pediatric intensive care unit (PICU) with (n=66) or without (n=120) TBI between 2012 and 2014. The risk factors, length of stay, and costs of NIs were determined. RESULTS Data for 186 patients were analyzed. One hundred and twenty patients were controls (54 males vs. 66 females), while 66 were cases (27 males vs. 39 females). Seventeen out of the 186 PICU patients had NIs. About 7.6% of TBI patients had infections whereas 10% of control groups had NIs (p=0.58). The most isolated microbial agent was Acinetobacterbaumannii (four cases). Thirteen (76.5%) out of the 17 infections were catheter-related bloodstream infections. The mean expenses per PICU patient were $762, with an additional cost of $2081 for patients with nosocomial contamination. CONCLUSION The use of catheters was the most critical risk factor for NIs in our study probably underestimated the cost for several reasons. Nevertheless, the findings supported our hypothesis about the additional burden of nosocomial spread on PICU patients. This study’s results should help provide evidence on cost-effectiveness or calculate the cost-benefit ratio of reducing NIs in children.

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confidence: 99%

Risk factors and cost of nosocomial infections in pediatric patients with traumatic brain injury

Incekoy Girgin

2023

North Clin Istanbul

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Evaluation of the Activities of Antimicrobial Agents on Multi-drug Resistant Gram Positive Bacteria Isolated from Intensive Care Units

Cited by 1 publication

References 20 publications

Risk factors and cost of nosocomial infections in pediatric patients with traumatic brain injury

Risk factors and cost of nosocomial infections in pediatric patients with traumatic brain injury

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