Evaluation of the difference between feline immunodeficiency virus (FIV)-infected and healthy cats by using clinicopathological parameters, oxidative stress, and total antioxidant power

Sakundech, Kanissarinn; Kullaya, A.; Aengwanich, Worapol

doi:10.1007/s00580-021-03222-3

Cited by 4 publications

(3 citation statements)

References 19 publications

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“…Previous reports found that cats co-infected with FeLV-FIV exhibited more severe clinical signs, with shorter survival times than FeLV or FIV alone (Spada et al 2018). Diagnosing infected cats based solely on clinical signs requires the use of additional diagnostic methods such as hemato-serology, immunochromatographic assay (FeLV/FIV Test kit) and PCR (Lacerda et al 2020;Capozza et al 2021;Sakundech et al 2021).…”

Section: Introductionmentioning

confidence: 99%

“…Currently, in Thailand, the method for examining FeLV/FIV in cats at animal clinics or hospitals involves using commercial test kits in conjunction with an assessment of hematology and serum biochemistry (Nedumpun et al 2015;Aiyaranoi et al 2018;Sakundech et al 2021). This study evaluated the incidence, hematology and serum biochemical changes among cats presented to the clinic that were naturally infected with FeLV and FIV in Thonburi district, Bangkok Province, Thailand.…”

Section: Introductionmentioning

confidence: 99%

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Hematological and Serum Biochemical Changes in Cats Naturally Infected with Feline Leukemia Virus and Feline Immunodeficiency Virus in Thonburi district, Bangkok, Thailand

2024

Int J Vet Sci

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Feline leukemia virus (FeLV )and feline immunodeficiency virus (FIV )are highly infectious, particularly among stray cats, with reported cases documented worldwide. This retrospective study analyzed cats infected with FeLV and FIV or co-infected with both in the Thonburi area of Bangkok from 2018 to 2022. A total of 830 cats were admitted to the animal clinic exhibiting clinical signs of depression, emaciation, ataxia, pale mucous membrane, gingivitis and corneal opacity. Twenty-nine cats tested positive for FeLV (3.49%), ranging in age from 2 to 60 months, while 16 cats tested positive for FIV (1.93%), ranging in age from 5 to 96 months and 30 cats tested positive for both FeLV and FIV (3.61%) with ages ranging from 4 to 108 months. None of the infected cats had received vaccination against FeLV or FIV and they were raised in an open husbandry system. Co-infection with FeLV and FIV was associated with a higher incidence of Mycoplasma spp. infection compared to cats infected with FeLV (P<0.001) or FIV (P<0.001) alone. Anemia was observed in co-infection with FeLV-FIV (24.24+9.97%), leukocytosis in co-infection with FeLV-FIV (21.3821.6610 3 cell/L), neutrophilia in FeLV (64.28+16.2810 3 cell/L), FIV (67.19+11.9210 3 cell/L) and FeLV+FIV (64.03+17.0910 3 cell/L). Thrombocytopenia was found in FeLV+FIV (247.13+148.9810 3 cell/L), with increased BUN in FeLV, FIV and FeLV+FIV, increased creatinine in FIV and elevated ALT in FeLV+FIV infected cats.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Hematological and Serum Biochemical Changes in Cats Naturally Infected with Feline Leukemia Virus and Feline Immunodeficiency Virus in Thonburi district, Bangkok, Thailand

2024

Int J Vet Sci

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“…The mechanism of FIV-induced cytopenia is likely to be multifactorial and result from direct or indirect suppression of hematopoiesis or secondary factors such as opportunistic infections and neoplasia. Direct infection of the bone marrow stromal cells with FIV and subsequent changes in cytokine expression can result in suppression of hematopoiesis (White et al, 2011;Sakundech et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

The Relationship of Clinicopathological Parameters and Formula for Predicting Malondialdehyde Level in Feline Immunodeficiency Virus (FIV) - infected Cats

Sakundech¹,

Aengwanich²

2022

J Hellenic Vet Med Soc

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The objective of this study was to investigate clinicopathological parameters, malondialdehyde and total antioxidant power for analyzing correlation and predicting malondialdehyde in plasma of feline immunodeficiency virus (FIV)-infected cats. Body condition score (BCS), mucous membrane color score (MMCS), vital signs, hematological parameters, malondialdehyde and ferric reducing antioxidant power (FRAP) of 20 FIV-infected cats were examined. The correlation and multiple regression model were then analyzed. The results revealed the following. The correlation between hemoglobin vs. packed cell volume (PCV), total red blood cell (TRBC) vs. PCV, TRBC vs. hemoglobin, mean corpuscular hemoglobin (MCH) vs. mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC) vs. MCH, body temperature vs. eosinophil, total white blood cell (TWBC) vs. eosinophil, MMCS vs. platelet, eosinophil vs. malondialdehyde, PCV vs. FRAP, hemoglobin vs. FRAP, TRBC vs. FRAP and TRBC vs. FRAP were significantly positive correlated between pairs of these parameters (P<0.05), while body temperature vs. MCV, TRBC vs. MCV, heart rate vs. platelet, heart rate vs. platelet were significantly negatively correlated between pairs of parameters (P<0.05). A formula for predicting malondialdehyde was Heart Rate (beats/minute) = 166.341 + 5.438*Hemoglobin (g/dl) + 0.0009*Total White Blood Cell (cell/ml) - 1152.48*Malondialdehyde (µmol/ml) (MSE=132.2540; r2=0.85). These results indicated that there were correlations between some clinicopathological parameters, malondialdehyde and total antioxidant power and a formula for predicting malondialdehyde levels in plasma of FIV-infected cat was obtained.

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The influence of ambient temperature and polyphenols from plant leaves on growth and the response to oxidative and nitrosative stress in African nightcrawler earthworm, Eudrilus eugeniae (Kinberg, 1867)

2023

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Evaluation of the difference between feline immunodeficiency virus (FIV)-infected and healthy cats by using clinicopathological parameters, oxidative stress, and total antioxidant power

Cited by 4 publications

References 19 publications

Hematological and Serum Biochemical Changes in Cats Naturally Infected with Feline Leukemia Virus and Feline Immunodeficiency Virus in Thonburi district, Bangkok, Thailand

Hematological and Serum Biochemical Changes in Cats Naturally Infected with Feline Leukemia Virus and Feline Immunodeficiency Virus in Thonburi district, Bangkok, Thailand

The Relationship of Clinicopathological Parameters and Formula for Predicting Malondialdehyde Level in Feline Immunodeficiency Virus (FIV) - infected Cats

The influence of ambient temperature and polyphenols from plant leaves on growth and the response to oxidative and nitrosative stress in African nightcrawler earthworm, Eudrilus eugeniae (Kinberg, 1867)

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