Evaluation of the Relationship between Diuresis and Kidney Function in Transplant Patients at Tabriz Imam Reza Hospital

Abstract

Introduction Kidney transplantation is the method of choice and a cost-effective treatment for ESRD patients, which has significantly reduced mortality and complications of the disease. In this study, we aim to investigate the effects of diuresis on renal function in transplant patients. The aim of this cross-sectional analysis is to find out the effects of diuresis on renal function in patients undergoing renal transplantation. Methods This cross-sectional study was conducted on kidney transplant patients at Tabriz Imam Reza Medical Education Center. During the study, patients were examined based on specific inclusion and exclusion criteria. Demographic information, including age, sex, morning weight the day before surgery, underlying disease, and duration of dialysis in years, was recorded. The study also included calculating the patients’ GFR using the CKD-EPI equation and determining its relationship with both recovery urinary output and 24-hour urinary output. Results This study included 49 patients who underwent kidney transplantation. The right and the left kidney was transplanted in 42 and 7 patients respectively. Present study showed that there was no significant relationship between the laboratory parameters of patients, including preoperative sodium, preoperative potassium, preoperative urea, preoperative creatinine, postoperative sodium, postoperative potassium, postoperative urea, postoperative creatinine, preoperative GFR, postoperative GFR, and diuresis of patients in the recovery room and 24 hours after surgery. Additionally, there was no significant relationship between indicators such as age and weight and the amount of diuresis of patients in the recovery room and 24 hours after the operation. Furthermore, this study did not find a significant difference in preoperative GFR, postoperative GFR, recovery output, and 24-hour output between patients with hypertension and the non-hypertensive group. Conclusion There was no significant relationship between demographic indicators and laboratory parameters and the amount of diuresis in patients. Additionally, the study found no significant difference in GFR and output between patients with hypertension and those without hypertension.