Evaluation of Transient or Permanent Congenital Hypothyroidism

Abstract

Congenital hypothyroidism is a common endocrine disease in children. In Türkiye, neonatal screening has been performed since 2007 with a cut-off Thyroid Stimulating Hormone (TSH) level of 5.5 mU/L. The initial treatment period is within the first 14 days. Reevaluation of thyroid function and thyroxine doses is necessary to determine whether the condition is permanent or transient congenital hypothyroidism. Numerous studies and proposals have been published on this topic. This article reviews the publications related to this subject.