Evaluation of Uric Acid Level and Glycemic Status in Type 2 Diabetic Patients in Rasht

Yaseri, Maryam; Mortazavi, Seyyede Sahere; Faraji, Niloofar

doi:10.32598/jgums.30.4.1786.1

Cited by 2 publications

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“…In this regard, studies indicated that BMI, waist circumference (WC), and waist-to-hip ratio (WHR) anthropometric index are comparable in predicting diabetes onset and following complications [ 9 , 10 ]. Moreover, patients with diabetes usually illustrated abnormalities in their laboratory findings [ 11 , 12 ]. The WHR associated with fasting blood sugar (FBS) levels, proteomic profile, and lipid profiles reflect its role in assessing metabolic health.…”

Section: Introductionmentioning

confidence: 99%

The association between waist-to-hip ratio (WHR) with diabetes in the PERSIAN Guilan cohort study population

Aghaei,

Joukar,

Hasanipour

et al. 2024

BMC Endocr Disord

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Background Waist circumference (WC), or waist-to-hip ratio (WHR), potentially offers a more accurate reflection of intra-abdominal fat accumulation and could serve as a superior predictor of type 2 diabetes mellitus (T2DM) risk compared to BMI. The current study investigated the relationship between WHR and its influencing factors among diabetes patients enrolled in the Prospective Epidemiological Research Studies in Iran (PERSIAN) Guilan Cohort study (PGCS). Method In this cross-sectional study of 10,520 participants, 2,531 had T2DM. Waist and hip circumference, body mass index (BMI), underlying diseases, and demographical data of participants were recorded. Also, fasting blood sugar (FBS), low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides (TG) were assessed. All data was analyzed using SPSS version 16; the significant level was < 0.05. Results The mean age of participants was 51.52 ± 8.90 years, and 39.9% had a BMI between 25 and 30 kg/m2. The prevalence of diabetes was 24.1% (n = 2531). About 7628 (72.5%) individuals had abnormal WHR, and 2072 (19.7%) were diabetics. Among patients with diabetes, abnormal WHR was significantly associated with age over 50, female gender, higher BMI, and lower LDL (P < 0.05). Conclusion The study showed a higher prevalence of abnormal WHR in diabetic patients. Abnormal WHR in patients with diabetes was significantly associated with age, gender, and BMI.

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Section: Introductionmentioning

confidence: 99%

The association between waist-to-hip ratio (WHR) with diabetes in the PERSIAN Guilan cohort study population

Aghaei,

Joukar,

Hasanipour

et al. 2024

BMC Endocr Disord

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“…High serum UA (SUA) levels, and hyperuricemia, are associated with gout, hypertension, kidney stones, kidney disease, cardiovascular complication, and metabolic syndrome [ 3 ]. Some diseases, such as metabolic syndrome and type 2 diabetes mellitus (T2DM), are often considered lifestyle-related diseases due to their pathological basis [ 4 – 6 ]. Diabetes has become an epidemic over the past few decades as one of the most significant global health emergencies of the 21st century.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of levels of uric acid and lipid profile in hospitalized patients with diabetes

et al. 2023

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Objective Diabetes is the most common metabolic disorder that leads to various complications, and among these complications, disruption in the lipid profile and serum uric acid (SUA) is one of the significant cases that can lead to the deterioration of the health status of patients with diabetes. So, we aimed to evaluate the level of SUA and lipid profiles in patients with diabetes. A total of 230 patients with diabetes who were admitted to Razi Hospital, Rasht, Iran, were enrolled in this study. Demographical data and clinical characteristics of the patients include gender, body mass index (BMI), duration of diabetes, history of smoking, FBS, HbA1c, SUA, Creatinine (Cr), Cholesterol (Chol), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TG), retinopathy, hypertension, ischemic heart disease (IHD), and microalbuminuria were recorded. All data were analyzed using the SPSS version 21 by a significant level < 0.05. Result According to our results, 70 were male, and 160 were female, with a mean age of 57.36 ± 8.05 years and a mean BMI of 28.10 ± 4.62. The most frequent comorbidities were hypertension, 67%. The serum level of FBS, HBA1c, SUA, Cr, Chol, LDL, HDL, and TG were 191.47 ± 71.66 mg/dL, 7.94 ± 1.21 mg/dL, 5.65 ± 1.95 mg/dL, 0.94 ± 0.16 mg/dL, 167.28 ± 45.22 mg/dL, 95.91 ± 37.03 mg/dL, 39.78 ± 10.44 mg/dL, and 186.75 ± 76.65 mg/dL, respectively. Only UA had a significant relationship with TG level (P < 0.05).

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Evaluation of Uric Acid Level and Glycemic Status in Type 2 Diabetic Patients in Rasht

Cited by 2 publications

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The association between waist-to-hip ratio (WHR) with diabetes in the PERSIAN Guilan cohort study population

The association between waist-to-hip ratio (WHR) with diabetes in the PERSIAN Guilan cohort study population

Evaluation of levels of uric acid and lipid profile in hospitalized patients with diabetes

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