Evaluation of Weight Reducing Effect of Evening Primrose Oil

Riaz,

doi:10.6000/1927-5951.2011.01.01.04

Cited by 2 publications

(1 citation statement)

References 31 publications

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“…Due to a lack of stability of most of the essential oils, new methods have been developed to improve their stability, among these is the encapsulation of the essential oils in liposomes (3). Liposomes are vesicles composed of concentric phospholipid bilayers (4). Due to their capability to deliver slow drug release, cutaneous targeting and extended transdermal delivery of drugs, liposomes have been reported to be promising drug carriers for antimicrobial therapy (3).…”

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Liposomes Containing Essential Oil of Eucalyptus camaldulensis Leaf

Moghimipour

Aghel

Mahmoudabadi

et al. 2012

Jundishapur J Nat Pharm Prod

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A B S T R A C T Background:The increased incidence of fungal resistance has necessitated the need to search for new antifungal agents. Objective: The main objectives of the present study were to investigate the effectiveness of the essential oil of Eucalyptus camaldulensis on dermatophytes growth and to formulate and characterize a liposomal gel loaded with the essential oil. Materials and Methods:The essential oil extracted from the leaves of E. camaldulensis was analyzed by GC-MS. The antifungal activity of this essential oil was determined against Microsporum canis, M. gypseum, Trichophyton rubrum and T. verrucosum, using the well diffusion method. Liposomes were prepared by the freeze-thaw method and evaluation of size distribution was performed using a particle size analyzer. The liposomal gel was prepared using 'hydroxethyl cellulose (HEC) as the gelling agent. The rheologic characteristics were determined by a Brookfield viscometer. Results:The results showed that the minimum inhibitory volume of the essential oil was 0.125 ml and 95 ± 0.57% of the essential oil was successfully entrapped in the liposomes. The main constituents of the essential oil detected by GC-MS were; phenol, 1, 8 cineole, limonene, alcohol, pinene and terpinen. Results of particle size determination showed a wide range from 40.5 to 298 nm for the different formulations. No significant thixotropy was observed in the rheogram of the formulated liposomal gel. Conclusion: Liposomal gel formulation of the essential oil may lead to improved antifungal activity.

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Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Liposomes Containing Essential Oil of Eucalyptus camaldulensis Leaf

Moghimipour

Aghel

Mahmoudabadi

et al. 2012

Jundishapur J Nat Pharm Prod

View full text Add to dashboard Cite

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Behavioral effects of citrus limon in rats

Khan

Riaz

2014

Metab Brain Dis

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Anxiety and depression are increasing worldwide, however these disorders may be managed by making healthier changes is dietary pattern, since there are evidences that diet rich in antioxidants and vitamins help reduce anxiety and depression. Hence present study was designed to evaluate the behavioral effects of Citrus limon in rats at three different doses i.e. 0.2, 0.4 and 0.6 ml/kg considered as low, moderate and high doses. Anxiolytic and antidepressant activities were specifically assessed twice during 15 days using open field test, elevated plus maze and forced swimming test. In open field test C. limon, revealed increase in distance travelled, number of central entries and number of rearing's at moderate dose, while in the elevated plus maze, number of open arm entries were found to be increased. Whereas in forced swimming test, there was decrease in duration of immobility and increase in duration of climbing. Thus results of present study suggest that C. limon at moderate dose have anxiolytic effect.

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Evaluation of Weight Reducing Effect of Evening Primrose Oil

Cited by 2 publications

References 31 publications

Preparation and Characterization of Liposomes Containing Essential Oil of Eucalyptus camaldulensis Leaf

Preparation and Characterization of Liposomes Containing Essential Oil of Eucalyptus camaldulensis Leaf

Behavioral effects of citrus limon in rats

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